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Home > Encyclopedia > 2-Bromo-3,5-dichloropyridine

2-Bromo-3,5-dichloropyridine

2-Bromo-3,5-dichloropyridine structure

2-Bromo-3,5-dichloropyridine 

structure
  • CAS No:

    14482-51-0

  • Formula:

    C5H2BrCl2N

  • Chemical Name:

    2-Bromo-3,5-dichloropyridine

  • Synonyms:

    2-BROMO-3,5-DICHLOROPYRIDINE;3,5-DICHLOROPYRIDIN-2-YL-BORONIC ACID;3,5-DICHLORO-2-BROMOPYRIDINE;AKOS BBS-00001365;PYRIDINE, 2-BROMO-3,5-DICHLORO-;2-BROMO-3,5-DICHLOROPYRIDUNE;3,5-DICHLORO-2-BROMOPYRIDINE 98+%;5-Dichloro-2-broMopyridine

  • Categories:

    Pharmaceutical Intermediates  >  Heterocyclic Compound

2-Bromo-3,5-dichloropyridine Basic Attributes

226.89

224.874756

-0

DTXSID90355733

2933399090

Characteristics

12.9

3.2

Pale brown Solid

1.848±0.06 g/cm3(Predicted)

40-42

243.3±35.0 °C(Predicted)

101.0±25.9 °C

1.597

5.17mmHg at 25°C

Safety Information

6.1

36/37/38-41-37/38-25

26-45-39

Xi,T

Irritant

P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P403+P233, P405, P501

H302

|Warning|H302 (25%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P403+P233, P405, and P501|Aggregated GHS information provided by 4 companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

2-Bromo-3,5-dichloropyridine Use and Manufacturing

K: 2-Amino-3, 5-dichloropyridine J (10 g, 61.3 mmol) was dissolved in an aqueous HBr solution (100 mL 48percent HBr, 200 niL HStep 1: 2-bromo-3, 5-dichloropyridine [0239] To a solution of 3, 5-dichloropyridin-2-amine (1.0 g, 6.2 mmol) in 40percent aqueous HBr (8 mL) was added dropwise bromine (2.8 g, 17 mmol) at -20°C. The orange suspension was stirred for 2hrs at -20°C, and followed by addition of the aqueous NaN02-bromo-3, 5-dichloropyridine. A 100 mL round-bottom flask equipped with a condenser was charged with 1.82 g of compound 71 (10.0 mmol) and propiononitrile (20 mL), 3.06 g TMSBr (20.0 mmol) was slowly added to the above solution. The reaction mixture was stirred at 100Raw material selection: 17.5 g of

Computed Properties

Molecular Weight:226.88
XLogP3:3.2
Hydrogen Bond Acceptor Count:1
Exact Mass:224.87477
Monoisotopic Mass:224.87477
Topological Polar Surface Area:12.9
Heavy Atom Count:9
Complexity:101
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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