pyrithione sodium
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pyrithione sodium
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CAS No:
15922-78-8
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Formula:
C5H5NOS.Na
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Chemical Name:
pyrithione sodium
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Synonyms:
Sodium pyridinethione;2(1H)-Pyridinethione, 1-hydroxy-, sodium salt;1-hydroxy-2-(1h)-pyridinethion sodium salt;1-hydroxy-2(1h)-pyridinethion sodium salt;1-hydroxy-2(1h)-pyridinethionato sodium;Pyridin-2-thiol-1-oxid, sodium salts;1-(Sodiooxy)-1,2-dihydropyridine-2-thione;1-Sodiooxy-2(1H)-pyridinethione
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CAS No:
Description
Pyrithione Sodium is the sodium salt form of pyrithione, a fungistatic and antimicrobial derivative of aspergillic acid. Although the exact mechanism of action remains to be fully elucidated, pyrithione sodium appears to interfere with membrane transport ultimately leading to a loss of metabolic control.
Safety Information
UT9800000
|Warning|H302+H312+H332 (49.5%): Harmful if swallowed, in contact with skin or if inhaled [Warning Acute toxicity, oral; acute toxicity, dermal; acute toxicity, inhalation]|P261, P264, P270, P271, P273, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P391, and P501|Aggregated GHS information provided by 898 companies from 28 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
The sodium salt of N-hydroxy-2-pyridinethiones has germicidal activity against yeasts and fungi. Sodium omadine is a 40% aqueous solution of sodium pyrithione. It is used in the metallurgical industry as a component of water-based metalworking fluids, of aceto-polyvinyl lattices, water-based printer’s ink, a lubricant for synthetic fibers, and antidandruff shampoos.
Drug Information
Substances that destroy fungi by suppressing their ability to grow or reproduce. They differ from FUNGICIDES, INDUSTRIAL because they defend against fungi present in human or animal tissues. (See all compounds classified as Antifungal Agents.)
1-hydroxypyridine-2-thione
pyrithione sodium Use and Manufacturing
Antimicrobial (topical).
2-Pyridinethiol, 1-oxide, sodium salt (1:1): ACTIVE
Computed Properties
Molecular Weight:149.15
Hydrogen Bond Acceptor Count:2
Exact Mass:148.99112921
Monoisotopic Mass:148.99112921
Topological Polar Surface Area:58.4
Heavy Atom Count:9
Complexity:162
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes
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