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Sodium pyrithione

Sodium pyrithione structure

Sodium pyrithione 

structure
  • CAS No:

    15922-78-8

  • Formula:

    C5H5NOS.Na

  • Chemical Name:

    Sodium pyrithione

  • Synonyms:

    2(1H)-Pyridinethione,1-hydroxy-,sodium salt (1:1);2(1H)-Pyridinethione,1-hydroxy-,sodium salt;2(1H)-Pyridinethione,1-hydroxy-,sodium deriv.;Sodium pyrithione;Sodium pyridinethione;Sodium Omadine;1-Hydroxypyridine-2-thione sodium salt;Omacide 24;Omadine Sodium;Omadine sodium salt;N-Hydroxy-2-thiopyridone sodium salt;Pyrithione sodium;AL 02725;N-Hydroxypyridine-2-thione sodium salt;Sodium 1-hydroxy-2(1H)-pyridinethionate;N-Hydroxy-2(1H)-pyridinethione sodium salt;Slaoff 28;116503-44-7;122333-48-6

  • Categories:

    Cosmetic Ingredient  >  Cosmetic Preservative

Description

Pyrithione Sodium is the sodium salt form of pyrithione, a fungistatic and antimicrobial derivative of aspergillic acid. Although the exact mechanism of action remains to be fully elucidated, pyrithione sodium appears to interfere with membrane transport ultimately leading to a loss of metabolic control.

Sodium pyrithione Basic Attributes

149.143

134.98800

240-062-8

6L3991491R

DTXSID3042390

C66498

Characteristics

58.4

2.00910

253.8ºC at 760mmHg

107.3ºC

0.00275mmHg at 25°C

Safety Information

UT9800000

|Warning|H302+H312+H332 (49.5%): Harmful if swallowed, in contact with skin or if inhaled [Warning Acute toxicity, oral; acute toxicity, dermal; acute toxicity, inhalation]|P261, P264, P270, P271, P273, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P391, and P501|Aggregated GHS information provided by 898 companies from 28 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

Substances that destroy fungi by suppressing their ability to grow or reproduce. They differ from FUNGICIDES, INDUSTRIAL because they defend against fungi present in human or animal tissues. (See all compounds classified as Antifungal Agents.)

1-hydroxypyridine-2-thione

Sodium pyrithione Use and Manufacturing

Uses

Antimicrobial (topical).

2-Pyridinethiol, 1-oxide, sodium salt (1:1): ACTIVE

Computed Properties

Molecular Weight:149.15
Hydrogen Bond Acceptor Count:2
Exact Mass:148.99112921
Monoisotopic Mass:148.99112921
Topological Polar Surface Area:58.4
Heavy Atom Count:9
Complexity:162
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

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