2-Chloro-3-methyl-5-nitropyridine
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2-Chloro-3-methyl-5-nitropyridine
structure -
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CAS No:
22280-56-4
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Formula:
C6H5ClN2O2
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Chemical Name:
2-Chloro-3-methyl-5-nitropyridine
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Synonyms:
Pyridine,2-chloro-3-methyl-5-nitro-;3-Picoline,2-chloro-5-nitro-;2-Chloro-3-methyl-5-nitropyridine;2-Chloro-5-nitro-3-picoline;NSC 63887;6-Chloro-5-methyl-3-nitropyridine
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CAS No:
2-Chloro-3-methyl-5-nitropyridine Basic Attributes
172.57
172.57
244-889-5
45ZN7UCB3M
63887
DTXSID70176827
29333999
Characteristics
58.7
2
Light beige to cream Crystalline Powder
1.4±0.1 g/cm3
47-48 °C
145.5 °C @ Press: 18 Torr
>110°C
1.576
2-8°C
Safety Information
Ⅲ
IRRITANT
UN 2811 6.1 / PGIII
3
36/37/38-20/21/22-41-37/38-22
37/39-26-39
Xn,Xi
P261-P280-P301 + P310-P305 + P351 + P338
H301-H315-H318-H335
|Danger|H301 (95.56%): Toxic if swallowed [Danger Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P310, P302+P352, P304+P340, P305+P351+P338, P310, P312, P321, P330, P332+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 135 companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
2-Chloro-3-methyl-5-nitropyridine Use and Manufacturing
Synthesis of the compound 20 The compound 19 (16.60 g, 0.1 mol) was added into 80mL of phosphorus oxychloride and heated under reflux for 8 h, and then distilled to remove excessive phosphorus oxychloride. The remaining solution was poured into 300g of broken ice, and 16.18 g of a black brown precipitate was precipitated with a yield of 87.1percent. The melting point is 44.5-45.8°C (M.P. 47-48°C was reported in the reference)[J.O.C. , 1949, 14, 328-332].
Computed Properties
Molecular Weight:172.57
XLogP3:2
Hydrogen Bond Acceptor Count:3
Exact Mass:172.0039551
Monoisotopic Mass:172.0039551
Topological Polar Surface Area:58.7
Heavy Atom Count:11
Complexity:159
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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2-Chloro-3-methyl-5-nitropyridine
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