4-AMINO-6-CHLOROPYRIMIDINE-5-CARBONITRILE
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4-AMINO-6-CHLOROPYRIMIDINE-5-CARBONITRILE
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CAS No:
60025-09-4
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Formula:
C5H3ClN4
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Chemical Name:
4-AMINO-6-CHLOROPYRIMIDINE-5-CARBONITRILE
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Synonyms:
4-AMINO-6-CHLOROPYRIMIDINE-5-CARBONITRILE;4-amino-6-chloro-pyrimidi...;4-Amino-6-chloro-5-cyanopyrimidine, 4-Amino-6-chloro-5-cyano-1,3-diazine;4-Amino-6-chloro-5-cyanopyrimidine;5-Pyrimidinecarbonitrile, 4-amino-6-chloro-;4-Amino-6-chloro-5-pyrimidinecarbonitrile;EOS-61673
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CAS No:
4-AMINO-6-CHLOROPYRIMIDINE-5-CARBONITRILE Basic Attributes
154.56
154.004623
DTXSID20483831
2933599090
4-AMINO-6-CHLOROPYRIMIDINE-5-CARBONITRILE Use and Manufacturing
4, 6-Dichloropyrimidine-5-carbonitrile (4.8 g, 27.59 mols) was suspended in 30 mL dioxane and the mixture was cooled at 0°C in an ice bath. Ammonia solution (7N in methanol, 20 mL, 140 mmol) was added dropwise over 20 min. The mixture was stirred at 0°C for 30 min. The solvent was evaporated and the crude was re-dissolved in tetrahydrofuran. A precipite was formed and filtered and washed with more tetrahydrofuran. The organics were evaporated under reduced pressure. The residue was purifed using a SP1
Computed Properties
Molecular Weight:154.56
XLogP3:1.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Exact Mass:154.0046238
Monoisotopic Mass:154.0046238
Topological Polar Surface Area:75.6
Heavy Atom Count:10
Complexity:162
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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4-AMINO-6-CHLOROPYRIMIDINE-5-CARBONITRILE
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