L-A-HYDROXYGLUTARIC ACID DISODIUM)
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L-A-HYDROXYGLUTARIC ACID DISODIUM)
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CAS No:
63512-50-5
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Formula:
C5H6O5Na2
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Chemical Name:
L-A-HYDROXYGLUTARIC ACID DISODIUM)
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Synonyms:
(S)-2-Hydroxypentanedioicacid;L-α-Hydroxyglutaricaciddisodiumsalt;(2S)-2-Hydroxyglutaric Acid Disodium Salt;s-2-Hydroxypentanedioic acid disodium salt;Pentanedioic acid,2-hydroxy-, disodium salt, (2S)-;(S)-α-Hydroxyglutaric Acid DisodiuM Salt;L-2-Hydroxyglutarate DisodiuM Salt;Pentanedioic acid, 2-hydroxy-, sodiuM salt (1:2)
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CAS No:
Description
L-2-Hydroxyglutaric acid disodium is an epigenetic modifier and putative oncometabolite in renal cancer. L-2-Hydroxyglutaric acid disodium can inhibit histone demethylases and hence promote histone methylation[1]. L-2-Hydroxyglutaric acid inhibits mitochondrial creatine kinase (Mi-CK) activity with Km and Ki of 2.52 mM and 11.13 mM, respectively[2].
L-A-HYDROXYGLUTARIC ACID DISODIUM) Use and Manufacturing
A potential inhibitor of glutamate carboxypeptidase.
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