20-Hydroxyeicosatetraenoic acid
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20-Hydroxyeicosatetraenoic acid
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CAS No:
79551-86-3
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Formula:
C20H32O3
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Chemical Name:
20-Hydroxyeicosatetraenoic acid
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Synonyms:
5,8,11,14-Eicosatetraenoic acid,20-hydroxy-,(5Z,8Z,11Z,14Z)-;5,8,11,14-Eicosatetraenoic acid,20-hydroxy-,(all-Z)-;(5Z,8Z,11Z,14Z)-20-Hydroxy-5,8,11,14-eicosatetraenoic acid;20-Hydroxyarachidonic acid;20-HETE;20-Hydroxy-5,8,11,14-eicosatetraenoic acid;20-Hydroxyeicosatetraenoic acid;ω-Hydroxyarachidonic acid;20-Hydroxyeicosa-5Z,8Z,11Z,14Z-tetraenoic acid
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CAS No:
Description
20-HETE(20-hydroxy Arachidonic Acid) is a potent vasoconstrictor produced in vascular smooth muscle (VSM) cells. It depolarizes VSM by blocking the open-state probability of Ca2+-activated K+-channels.IC50 Value:Target: 20-Hydroxyeicosatetraenoic acid (20-HETE) is a cytochrome P450-derived arachidonic acid metabolite that has been shown to increase smooth muscle contractions and proliferation, stimulate endothelial dysfunction and activation and promote hypertension. in vitro: Addition o
Safety Information
UN11703/PG2
3
11-36/37/38
16-26-36
F,Xi
P210-P305 + P351 + P338-P370 + P378-P403 + P235
H225-H319
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