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Tipelukast

Tipelukast structure

Tipelukast 

structure
  • CAS No:

    125961-82-2

  • Formula:

    C29H38O7S

  • Chemical Name:

    Tipelukast

  • Synonyms:

    tipelukast;4-[6-acetyl-3-[3-[(4-acetyl-3-hydroxy-2-propylphenyl)sulfanyl]propoxy]-2-propylphenoxy]butanoic acid;KCA 757;MN 001 (pharMaceutical);MN-001 (Tipelukast)

Description

Tipelukast (KCA 757) is a sulfidopeptide leukotriene receptor antagonist, an orally bioavailable anti-inflammatory agent and used for the treatment of asthma.


Tipelukast is an aromatic ketone.|Tipelukast is under investigation for the treatment of IPF and Idiopathic pulmonary fibrosis.

Tipelukast Basic Attributes

530.67282

530.233826

08379P260O

Characteristics

135

7.85

1.22

735.3±60.0 °C(Predicted)

398.5±32.9 °C

1.582

Drug Information

4-(6-acetyl-3-(3-(4-acetyl-3-hydroxy-2-propylphenylthio)propoxy)-2-propylphenoxy)butyric acid

Computed Properties

Molecular Weight:530.7
XLogP3:6.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:17
Exact Mass:530.23382472
Monoisotopic Mass:530.23382472
Topological Polar Surface Area:135
Heavy Atom Count:37
Complexity:714
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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