 Home > Encyclopedia > 2-Arachidonylglycerol

2-Arachidonylglycerol

2-Arachidonylglycerol structure

CAS No:
53847-30-6
Formula:
C23H38O4
Chemical Name:
2-Arachidonylglycerol
Synonyms:
5,8,11,14-Eicosatetraenoic acid,2-hydroxy-1-(hydroxymethyl)ethyl ester,(5Z,8Z,11Z,14Z)-;5,8,11,14-Eicosatetraenoic acid,2-hydroxy-1-(hydroxymethyl)ethyl ester,(all-Z)-;2-Arachidonylglycerol;2-Monoarachidonoylglycerol;75656-17-6
Categories:
Biochemical Engineering > Inflammation Mediators

Description

2-Arachidonoylglycerol is a second endogenous cannabinoid ligand in the central nervous system.

Solid

2-arachidonoylglycerol is an endocannabinoid and an endogenous agonist of the cannabinoid receptors (CB1 and CB2). It is an ester formed from omega-6-arachidonic acid and glycerol. It has a role as a human metabolite. It is an endocannabinoid and a 2-acylglycerol 20:4. It derives from an arachidonic acid.

2-Arachidonylglycerol Basic Attributes

Molecular Weight：

378.55

Exact Mass：

378.55

EC Number：

200-835-2

UNII：

8D239QDW64

HScode：

2916190090

Characteristics

PSA：

66.8

XLogP3：

6.24

Appearance：

acetonitrile solution

Density：

1.0±0.1 g/cm3

Boiling Point：

508.6±50.0 °C at 760 mmHg

Flash Point：

2 °C

Refractive Index：

1.508

Storage Conditions：

−20°C

Safety Information

Transport codes：

UN 1648 3/PG 2

wgk germany：

hazard class code：

11-20/21/22-36

safety instructions：

26-36/37-16

Marks：

F,Xn

Precautionary statement(s)：

P210-P261-P280-P305 + P351 + P338-P370 + P378-P403 + P235

Hazard Statements：

H225-H302 + H312 + H332-H319

Drug Information

MeSH：

Compounds that interact with and stimulate the activity of CANNABINOID RECEPTORS. (See all compounds classified as Cannabinoid Receptor Agonists.)

MeSH Entry Terms：

2-arachidonoyl-glycerol

2-Arachidonylglycerol Use and Manufacturing

Uses

2-Arachidonoylglycerol is a major endocannabinoid, which can inhibit synaptic transmission by presynaptic cannabinoid CB1 receptors. It plays an inhibitory role in the bombesin-induced activation of central adrenomedullary outflow in rats.

Use Classification：

Lipids -> Glycerolipids [GL] -> Monoradylglycerols [GL01] -> Monoacylglycerols [GL0101]

Computed Properties

Molecular Weight:378.5
XLogP3:5.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:18
Exact Mass:378.27700969
Monoisotopic Mass:378.27700969
Topological Polar Surface Area:66.8
Heavy Atom Count:27
Complexity:445
Defined Bond Stereocenter Count:4
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Learn More Other Chemicals

10-hydroxy-10-(3-octa-2,5-dienyloxiran-2-yl)deca-5,8-dienoic acid

103188-12-1
(5E,9E)-8-hydroxy-10-[3-[(2E,5E)-octa-2,5-dienyl]oxiran-2-yl]deca-5,9-dienoic acid

103188-13-2
(4-benzamidophenyl) (Z)-7-[(1R,2R,3R)-3-hydroxy-2-(2-hydroxy-3-phenoxypropoxy)-5-oxocyclopentyl]hept-4-enoate

106342-69-2
20-dimethyl-7-thiaprostaglandin E1 methyl ester Formula

111037-12-8
11-deoxyprostaglandin E1 4-hydroxyphenyl ester Formula

114495-95-3
16,18-ethano-20-ethyl-6-oxoprostaglandin E1 leucinamide Formula

115288-30-7
(5S,6Z,8E,10E,12R,14Z)-5,12-Dihydroxy-20-oxo-6,8,10,14-eicosatetraenoic acid Structure

115609-68-2
EP 171 Structure

115825-93-9
What is 5,12,19-trihydroxyicosa-6,8,10,14-tetraenoic acid

117605-61-5
What is (E)-7-[5-chloro-2-[(E)-3-cyclohexyl-3-hydroxyprop-1-enyl]-3-hydroxycyclopentyl]hept-5-enoic acid

117708-11-9

Hot Searches: ethyl acetoacetate; 1-bromo-2-methylpropane; fusidic acid cream; iodide formula; formula for ammonia sulfate; magnesium nitride

Guide of 2-Arachidonylglycerol

Description
Basic Attributes
Characteristics
Safety Information
Drug Information
Use and Manufacturing
Computed Properties
Learn More Other Chemicals

2-Arachidonylglycerol

SDS

Request for Quotation



Feedback & Suggestions

Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.