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Home > Encyclopedia > 3-Hydroxypropyl N,N-bis(2-chloroethyl)phosphorodiamidate

3-Hydroxypropyl N,N-bis(2-chloroethyl)phosphorodiamidate

3-Hydroxypropyl N,N-bis(2-chloroethyl)phosphorodiamidate structure

3-Hydroxypropyl N,N-bis(2-chloroethyl)phosphorodiamidate 

structure
  • CAS No:

    52336-54-6

  • Formula:

    C7H17Cl2N2O3P

  • Chemical Name:

    3-Hydroxypropyl N,N-bis(2-chloroethyl)phosphorodiamidate

  • Synonyms:

    Phosphorodiamidic acid,N,N-bis(2-chloroethyl)-,3-hydroxypropyl ester;3-Hydroxypropyl N,N-bis(2-chloroethyl)phosphorodiamidate;O-(3-Hydroxypropyl)-N,N-bis(2-chloroethyl)phosphorodiamidate;NSC 153182;Alcophosphamide;NSC 227248;60342-84-9

Description

Alcophosphamide is a nitrogen mustard.

3-Hydroxypropyl N,N-bis(2-chloroethyl)phosphorodiamidate Basic Attributes

279.102

279.10

153182|227248

Characteristics

75.8

-0.2

1.356±0.06 g/cm3(Predicted)

413.8ºC at 760 mmHg

204ºC

1.51

Drug Information

alcophosphamide

3-Hydroxypropyl N,N-bis(2-chloroethyl)phosphorodiamidate Use and Manufacturing

Alcophosphamide is a metabolite of the chemotherapeutic agent Cyclophosphamide (C988580).

Computed Properties

Molecular Weight:279.10
XLogP3:-0.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:9
Exact Mass:278.0353848
Monoisotopic Mass:278.0353848
Topological Polar Surface Area:75.8
Heavy Atom Count:15
Complexity:203
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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