alpha-[2-(diisopropylamino)ethyl]-alpha-isobutylpyridine-2-acetamide
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alpha-[2-(diisopropylamino)ethyl]-alpha-isobutylpyridine-2-acetamide
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CAS No:
78833-03-1
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Formula:
C19H33N3O
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Chemical Name:
alpha-[2-(diisopropylamino)ethyl]-alpha-isobutylpyridine-2-acetamide
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Synonyms:
alpha-[2-(diisopropylamino)ethyl]-alpha-isobutylpyridine-2-acetamide;2-[2-(Diisopropylamino)ethyl]-4-methyl]-2-(2-pyridyl)pentanamide;a-[2-[Bis(1-methylethyl)amino]ethyl]-a-(2-methylpropyl)-2-pyridineacetamide;CM-7857;ME-3202;Pentisomide;Propisomide;α-[2-[Bis(1-methylethyl)amino]ethyl]-α-(2-methylpropyl)-2-pyridineacetamide
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CAS No:
alpha-[2-(diisopropylamino)ethyl]-alpha-isobutylpyridine-2-acetamide Basic Attributes
319.48482
319.48
2789895
Off-White to Pale Brown
Characteristics
59.2
4.06000
0.987±0.06 g/cm3(Predicted)
108-1090C
460.5±45.0 °C(Predicted)
15.87±0.50(Predicted)
Refrigerator
Drug Information
Drugs that block nerve conduction when applied locally to nerve tissue in appropriate concentrations. They act on any part of the nervous system and on every type of nerve fiber. In contact with a nerve trunk, these anesthetics can cause both sensory and motor paralysis in the innervated area. Their action is completely reversible. (From Gilman AG, et. al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed) Nearly all local anesthetics act by reducing the tendency of voltage-dependent sodium channels to activate. (See all compounds classified as Anesthetics, Local.)|Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade. (See all compounds classified as Anti-Arrhythmia Agents.)
2-(2-(diisopropylamino)ethyl)-4-methyl-2-(2-pyridyl)pentamide
alpha-[2-(diisopropylamino)ethyl]-alpha-isobutylpyridine-2-acetamide Use and Manufacturing
Sodium channel blocker; derivative of disopyramide. Antiarrhythmic (class I)
Computed Properties
Molecular Weight:319.5
XLogP3:3.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:9
Exact Mass:319.262362685
Monoisotopic Mass:319.262362685
Topological Polar Surface Area:59.2
Heavy Atom Count:23
Complexity:360
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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alpha-[2-(diisopropylamino)ethyl]-alpha-isobutylpyridine-2-acetamide
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