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4′,6-Diamidino-2-phenylindole dihydrochloride

4′,6-Diamidino-2-phenylindole dihydrochloride structure

CAS No:
28718-90-3
Formula:
C16H15N5.2ClH
Chemical Name:
4′,6-Diamidino-2-phenylindole dihydrochloride
Synonyms:
1H-Indole-6-carboximidamide,2-[4-(aminoiminomethyl)phenyl]-,hydrochloride (1:2);Indole-6-carboxamidine,2-(p-amidinophenyl)-,dihydrochloride;1H-Indole-6-carboximidamide,2-[4-(aminoiminomethyl)phenyl]-,dihydrochloride;6-Amidino-2-(4-amidinophenyl)indole dihydrochloride;4′,6-Diamidino-2-phenylindole dihydrochloride;FxCycle Violet;DAPI;33047-44-8
Categories:
Specialty Chemicals

Description

DAPI dihydrochloride (4',6-diamidino-2-phenylindole) is a fluorescent stain by binding in the minor grove of A-T rich sequences of DNA.

4′,6-Diamidino-2-phenylindole dihydrochloride Basic Attributes

Molecular Weight：

350.25

Exact Mass：

349.086090

EC Number：

249-186-7

UNII：

76BFW26YJO

DSSTox ID：

DTXSID40182879

HScode：

2933990090

Characteristics

PSA：

116

XLogP3：

5.60710

Appearance：

Clear powder

Density：

1.41g/cm3

Melting Point：

>300°C (dec.)

Boiling Point：

545.4ºC at 760mmHg

Flash Point：

283.6ºC

Water Solubility：

H2O: 10 mg/mL heat or sonication may be required. Solutions stored in the dark at room temperature or 4 °C should be stable for 2 to 3 weeks.

Storage Conditions：

−20°C

Vapor Pressure：

5.96E-12mmHg at 25°C

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

36/37/38-20/21/22

safety instructions：

26-36-24/25-22-37/39

RTECS Number：

NL5995050

Marks：

Xi,Xn

Precautionary statement(s)：

P261, P264, P271, P272, P280, P302+P352, P304+P340, P312, P321, P332+P313, P333+P313, P362, P363, P403+P233, P405, P501

Hazard Statements：

H315

GHS Classification：

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P272, P280, P302+P352, P304+P340, P312, P321, P332+P313, P333+P313, P362, P363, P403+P233, P405, and P501|Aggregated GHS information provided by 122 companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

4′,6-Diamidino-2-phenylindole dihydrochloride Use and Manufacturing

DAPI is used for photofootprinting of DNA, to detect annealed probes in blotting applications by specifically visualizing the double-stranded complex and as a cell permeable fluorescent minor groove-binding probe for DNA. For staining DNA in agarose gels

Computed Properties

Molecular Weight:350.2
Hydrogen Bond Donor Count:7
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:349.0861010
Monoisotopic Mass:349.0861010
Topological Polar Surface Area:116
Heavy Atom Count:23
Complexity:413
Covalently-Bonded Unit Count:3
Compound Is Canonicalized:Yes

Recommended Suppliers of 4′,6-Diamidino-2-phenylindole dihydrochloride

HANGZHOU LEAP CHEM CO., LTD. Contact Supplier

CN
5 YRS

Business licensed

Trader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives

4,6-Diamidino-2-phenylindole dihydrochloride

CAS No.: 28718-90-3

Content: 99.00%

Inquiry
Wuhan Pnq Int Trade Co., Ltd Contact Supplier

CN
3 YRS

Business licensed

Trader Supplier of Apigenin,PQQ,NMNH

Chinese pharmaceutical manufacture PNQ supply 4',6-Diamidino-2-phenylindole dihydrochloride

Unit Price: $100 /UNIT EXW

CAS No.: 28718-90-3

Grade: Chemical Grade

Content: 99%

Inquiry
Henan Lihao Chem Plant Limited Contact Supplier

CN
5 YRS

Business licensed

Trader Supplier of PVC resin,pvc paste resin,melamine

high quality 2-(4-carbamimidoylphenyl)-1h-indole-6-carboximidamide 99% transparent liquid KANBEI

CAS No.: 28718-90-3

Grade: Industrial Grade

Content: 99%

Inquiry

Latest News on 4′,6-Diamidino-2-phenylindole dihydrochloride

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Guide of 4′,6-Diamidino-2-phenylindole dihydrochloride

Description
Basic Attributes
Characteristics
Safety Information
Use and Manufacturing
Computed Properties
Recommended Suppliers
Latest News
Learn More Other Chemicals

4′,6-Diamidino-2-phenylindole dihydrochloride

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