Alrestatin
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Alrestatin
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CAS No:
51411-04-2
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Formula:
C14H9NO4
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Chemical Name:
Alrestatin
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Synonyms:
1H-Benz[de]isoquinoline-2(3H)-acetic acid,1,3-dioxo-;1,3-Dioxo-1H-benz[de]isoquinoline-2(3H)-acetic acid;AY 22284;Alrestatin;HIC 016G;[1,3-Dioxo-1H,3H-benz[de]isoquinolin-2-yl]acetic acid;NSC 299132;(1,3-Dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)acetic acid;2-(1,3-Dioxobenzo[de]isoquinolin-2-yl)acetic acid
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CAS No:
Description
Alrestatin is an inhibitor of aldose reductase, an enzyme involved in the pathogenesis of complications of diabetes mellitus, including diabetic neuropathy.
Safety Information
|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501|The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.
Drug Information
Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. (See all compounds classified as Enzyme Inhibitors.)|Agents that inhibit the actions of the parasympathetic nervous system. The major group of drugs used therapeutically for this purpose is the MUSCARINIC ANTAGONISTS. (See all compounds classified as Parasympatholytics.)
alrestatin
Computed Properties
Molecular Weight:255.22
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:255.05315777
Monoisotopic Mass:255.05315777
Topological Polar Surface Area:74.7
Heavy Atom Count:19
Complexity:403
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
