3-Amino-5-tert-butylisoxazole
-
3-Amino-5-tert-butylisoxazole
structure -
-
CAS No:
55809-36-4
-
Formula:
C7H12N2O
-
Chemical Name:
3-Amino-5-tert-butylisoxazole
-
Synonyms:
TIMTEC-BB SBB005492;5-TERT-BUTYLISOXAZOL-3-AMINE;5-TERT-BUTYL-ISOXAZOL-3-YLAMINE;5-(1,1-dimethylethyl)-3-isoxazolamine;3-AMINO-5-TERT-BUTYLISOXAZOLE;3-AMINO-5-T-BUTYLISOXAZOLE;3-Amino-5-tert-butylisoxazole,97%;3-Amino-5-tert-butylisoxazole 97%
- Categories:
-
CAS No:
3-Amino-5-tert-butylisoxazole Basic Attributes
140.18
140.094955
1100990
-0
DTXSID3073559
2934999090
Safety Information
IRRITANT
3
22-36/37/38-37/38-36
26-36-37
Xn,Xi
Irritant
P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, P501
H302
|Warning|H302 (97.52%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 202 companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
3-Amino-5-tert-butylisoxazole Use and Manufacturing
4, 4-dimethyl-3-oxopentanenitrile (3 g, 23.97 mmol) was dissolved in distilled water, stirred, and added with NaOH (1.06 g, 26.4 mmol) and NH4, 4-dimethyl-3-oxopentanenitrile (3 g, 23.97 mmol) was dissolved in distilled water, stirred, and added with NaOH (1.06 g, 26.4 mmol) and NHTo a solution of pivaloylacetonitrile (3 g, 23.97 mmol) in water (20 mL), NaOH (1.06 g, 26.4 mmol) and hydroxylamine hydrochloride (1.83 g, 26.4 mmol) were added continuously with stirring. The resulting solution was stirred for approximately 30 min at room temperature, and the pH adjusted to 10–11 with 1 M NaOH. After stirring for 10 h or more at 50 °C, the mixture was cooled and washed two to three times with carbon tetrachloride. The aqueous layer was acidified with concentrated HC1 until the pH = 4–5, and then further stirred for approximately 3 h at 50 °C. The reaction mixture was cooled to room temperature, and adjusted to pH 12 by adding an aqueous solution of 1 N NaOH. The resulting solid was filtered, washed with distilled water, and driedin air to obtain compound 25s as a white solid (2.0 g, yield: 70percent).
Amination of aryl bromides catalyzed by Pd(dba)3 (Aldrich Catalog No. 328774) and Xantphos (Aldrich Catalog No. 526460).1
Computed Properties
Molecular Weight:140.18
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:140.094963011
Monoisotopic Mass:140.094963011
Topological Polar Surface Area:52
Heavy Atom Count:10
Complexity:119
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Recommended Suppliers of 3-Amino-5-tert-butylisoxazole
-
![China]()
CN
5 YRS
Business licensedTrader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives -
![China]()
CN
8 YRS
Business licensed Certified factoryManufactory Supplier of Biochemicals Ingredients,Vitamin Amino Acid Ingredients,Cosmestic Ingredients,Pharma Chemicals,Organic Fine Chemicals,Food Nutrient Ingredients,Natural Plant Ingredients,APIS Intermidiates,Daily Chemicals,Agricultural Chemicals,Surfactant Chemicals,Ultraviolet Absorbents,Antioxidant Ingredients,Scientific Research Chemical,Flavors and Fragrances ChemicalsInquiryCAS No.: 55809-36-4Grade: Pharmaceutical GradeContent: 99% -
![China]()
CN
5 YRS
Business licensedTrader Supplier of PVC resin,pvc paste resin,melamineInquiryCAS No.: 55809-36-4Grade: Industrial GradeContent: 99% -
![China]()
CN
8 YRS
Business licensed Certified factoryManufactory Supplier of Anti-tumor categories,Cardiovascular,Anti-Diabetes Class -
![China]()
CN
5 YRS
Business licensed Certified factoryManufactory Supplier of Pharmaceutical intermedaite,Agricultural chemical intermediateInquiryCAS No.: 55809-36-4Grade: Pharmaceutical GradeContent: 99.0%
Learn More Other Chemicals
-
3-(3-CHLOROPROPYLCARBAMOYL)BENZENEBORONIC ACID
874288-10-5
-
3-Pyridinecarboxylic acid, 2,6-dichloro-, ethyl ester
58584-86-4
-
(+)-Mesembrenone
468-54-2
-
1,5-Methano-1H-3-benzazepine, 2,3,4,5-tetrahydro-, hydrochloride (1:1) Formula
230615-52-8
-
(4-acetyloxyphenyl)-(4-acetyloxyphenyl)imino-oxidoazanium Formula
79030-44-7
-
1-(4-Methoxy-phenyl)-2,5-dimethyl-1H-pyrrole-3-carbaldehyde Formula
347331-30-0
-
2,2'-DIAMINODIPHENYL SULFIDE Structure
5873-51-8
-
AC-ARG-PHE-MET-TRP-MET-ARG-NH2 Structure
152274-65-2
-
What is 1,1-Dimethylethyl 2-bromo-2-methylpropanoate
23877-12-5
-
What is 1,3-Dichloro-2,4-difluorobenzene
36556-37-3