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Home > Encyclopedia > 4-Amino-2-methoxyphenol

4-Amino-2-methoxyphenol

4-Amino-2-methoxyphenol structure

4-Amino-2-methoxyphenol 

structure
  • CAS No:

    52200-90-5

  • Formula:

    C7H9NO2

  • Chemical Name:

    4-Amino-2-methoxyphenol

  • Synonyms:

    Phenol,4-amino-2-methoxy-;Guaiacol,4-amino-;4-Amino-2-methoxyphenol;4-Aminoguaiacol;2-Methoxy-4-aminophenol;4-Hydroxy-3-methoxyaniline;NSC 405988;3-Methoxy-4-hydroxyaniline

  • Categories:

    Pharmaceutical Intermediates  >  Bulk Drug Intermediates

Description

Dark-Brown Crystalline Solid

4-Amino-2-methoxyphenol Basic Attributes

139.16

139.15

1592732-453-0

2SA6Z96YSE

405988

DTXSID00200245

2922509090

Characteristics

55.5

0.1

Dark-brown crystalline solid

1.2±0.1 g/cm3

177-178 °C

308.1°C at 760 mmHg

140.1±23.7 °C

1.600

Safety Information

IRRITANT

NONH for all modes of transport

22

SJ6072000

Xn

P264, P270, P280, P301+P312, P302+P352, P305+P351+P338, P321, P330, P332+P313, P337+P313, P362, P501

H302

|Warning|H302+H312+H332 (33.33%): Harmful if swallowed, in contact with skin or if inhaled [Warning Acute toxicity, oral; acute toxicity, dermal; acute toxicity, inhalation]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P403+P233, P405, and P501|Aggregated GHS information provided by 3 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

4-Amino-2-methoxyphenol Use and Manufacturing

A mixture of 2-methoxy-4-nitrophenol (3.00 g, 17.7 mmol), 10percent palladium carbon (300 mg), THF (100 ML) and methanol (100 ML) was stirred under hydrogen atmosphere at room temperature for 4 hours.

Computed Properties

Molecular Weight:139.15
XLogP3:0.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:139.063328530
Monoisotopic Mass:139.063328530
Topological Polar Surface Area:55.5
Heavy Atom Count:10
Complexity:108
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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