2-Amino-5-(aminomethyl)-1-naphthalenesulfonic acid

Amino compounds of the formula (6) 2-amino-5-aminomethyl-naphthalene-1-sulfonic acid, 2-amino-5-N-methylaminomethyl-naphthalene-1-sulfonic acid, 2-amino-6-aminomethyl-naphthalene-1-sulfonic acid, 2-amino-6-N-methylaminomethyl-naphthalene-1-sulfonic acid.EXAMPLE 90 223 Parts of 2-amino-1-sulpho-naphthalene are introduced into 1, 000 parts by volume of concentrated sulphuric acid at 15-20. Thereafter 153 parts of N-methylolbenzamide are added and the mixture is stirred for 24 hours at room temperature. The solution is poured out onto 3, 000 parts of ice. The precipitate is filtered off and washed with water. The moist paste is stirred up with 1, 500 parts of water, neutralised and after addition of 250 parts by volume of concentrated sodium hydroxide solution (d = 1, 48) the mixture is warmed to 170 in an autoclave for 2 hours. After cooling the clear solution obtained is adjusted to pH 7 by addition of concentrated hydrochloric acid whereby the 2-amino-1-sulpho-5-aminomethyl-naphthalene precipitates in form of the betaine. The precipitate is filtered off. The amine content of the moist paste is found out by determination of the nitrite value.

Molecular Weight:252.29
XLogP3:-1.6
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:252.05686342
Monoisotopic Mass:252.05686342
Topological Polar Surface Area:115
Heavy Atom Count:17
Complexity:365
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes