Product
Supplier
Encyclopedia
Inquiry
Home > Encyclopedia > AMINO ACID HYDROXAMATES DL-SERINE HYDROXAMATE

AMINO ACID HYDROXAMATES DL-SERINE HYDROXAMATE

AMINO ACID HYDROXAMATES DL-SERINE HYDROXAMATE structure

AMINO ACID HYDROXAMATES DL-SERINE HYDROXAMATE 

structure
  • CAS No:

    55779-32-3

  • Formula:

    C3H8N2O3

  • Chemical Name:

    AMINO ACID HYDROXAMATES DL-SERINE HYDROXAMATE

  • Synonyms:

    AMINO ACID HYDROXAMATES DL-SERINE HYDROXAMATE;rac-(R*)-2-Amino-3-hydroxypropanehydroxamic acid;DL-Serine hydroxaMate seryl-tRNA synthetase inhibitor;(Z)-2-aMino-N,3-dihydroxypropaniMidic acid;SHX;DL-SERINE HYDROXAMATE, SERYL-TRNA SY;dl-serine hydroxamate;Propanamide, 2-amino-N,3-dihydroxy-

Description

Serine hydroxamate is a hydroxamic acid obtained by formal condensation of the carboxy group of serine with the amino group of hydroxylamine. It has a role as an EC 6.1.1.11 (serine--tRNA ligase) inhibitor. It is a hydroxamic acid and a serine derivative.

AMINO ACID HYDROXAMATES DL-SERINE HYDROXAMATE Basic Attributes

120.11

120.11

517349

White to off-white

Characteristics

95.6

-2.5

−20°C

-20°C

Safety Information

3

Drug Information

serine hydroxamate

AMINO ACID HYDROXAMATES DL-SERINE HYDROXAMATE Use and Manufacturing

Serine has been used as an inhibitor of seryl-tRNA synthetase. DL-Serine hydroxamate is used to induce metabolic synthesis of guanosine 3′-diphosphate 5′-diphosphate (ppGpp) inE. coliby amino acid starvation. It is also used to synchronize cell cycle inE. colicultures by inhibition of tRNA charging.

Computed Properties

Molecular Weight:120.11
XLogP3:-2.5
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:120.05349212
Monoisotopic Mass:120.05349212
Topological Polar Surface Area:95.6
Heavy Atom Count:8
Complexity:84.6
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Scan the QR Code to Share

Feedback & Suggestions
Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.