Amitivir
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Amitivir
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CAS No:
111393-84-1
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Formula:
C3H2N4S
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Chemical Name:
Amitivir
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Synonyms:
1,3,4-thiadiazol-2-ylcyanamide;LY 217896;LY 253963;LY-217896;LY-253963;LY217896;LY253963;Amitivir;UNII-R4KR9A9165;N-(1,3,4-thiadiazol-2-yl)cyanamide
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CAS No:
Description
Amitivir is a secondary amine.|Amitivir is an inhibitor of inosine monophosphate dehydrogenase with activity against several influenza A and B viruses. Amitivir inhibits the conversion of inosine monophosphate to xanthosine monophosphate, the rate-limiting step in the de novo biosynthesis of guanine nucleotides, leading to inhibition of cell proliferation.
Computed Properties
Molecular Weight:126.14
XLogP3:0.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:126.00001725
Monoisotopic Mass:126.00001725
Topological Polar Surface Area:89.8
Heavy Atom Count:8
Complexity:116
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes