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ANDROGRAPHOLIDE, DEOXY-

ANDROGRAPHOLIDE, DEOXY- structure

CAS No:
79233-15-1
Formula:
C20H30O4
Chemical Name:
ANDROGRAPHOLIDE, DEOXY-
Synonyms:
Deoxyandrographolide;4-[2-[(4aS,5R,6R,8aR)-6-hydroxy-5-(hydroxymethyl)-2,5,8a-trimethyl-3,4,4a,6,7,8-hexahydronaphthalen-1-yl]ethyl]-2H-furan-5-one;CHEMBL4454267;DTXSID60616868;HY-N0857;9342AF;ZINC21992845;AKOS015965180;3-(4-Chlorobenzenesulfonyl)butyricacid;CS-3655
Categories:
Pharmaceutical Intermediates > Bulk Drug Intermediates

Description

Deoxyandrographolide is a natural compound extracted from A. paniculata; potently inhibit the growth of liver (HepG2 and SK-Hep1) and bile duct (HuCCA-1 and RMCCA-1) cancer cells.IC50 value:Target: Anticancer natural compoundin vitro: Treatment with 14-DAG activated AMPK through induction of cyclic AMP-protein kinase A pathway. 14-DAG controlled ethanol-induced hepatosteatosis by interfering with dysregulation of lipid metabolism. In conclusion, our results indicated that 14-DAG was capa

ANDROGRAPHOLIDE, DEOXY- Basic Attributes

Molecular Weight：

334.45

Exact Mass：

334.214417

EC Number：

2017-001-1

Characteristics

PSA：

66.76000

XLogP3：

2.55

Density：

1.1±0.1 g/cm3

Boiling Point：

511.7±50.0 °C at 760 mmHg

Flash Point：

178.2±23.6 °C

Refractive Index：

1.535