Aptiganel
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Aptiganel
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CAS No:
137159-92-3
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Formula:
C20H21N3
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Chemical Name:
Aptiganel
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Synonyms:
Guanidine,N-(3-ethylphenyl)-N-methyl-N′-1-naphthalenyl-;N-(3-Ethylphenyl)-N-methyl-N′-1-naphthalenylguanidine;Aptiganel;1-(3-Ethylphenyl)-1-methyl-2-naphthalen-1-ylguanidine
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CAS No:
Characteristics
41.6
4.6
white solid
1.08g/cm3
490.9ºC at 760 mmHg
250.7ºC
1.599
H2O: 17 mg/mL, soluble
2-8°C
8.81E-10mmHg at 25°C
Drug Information
Drugs that bind to but do not activate excitatory amino acid receptors, thereby blocking the actions of agonists. (See all compounds classified as Excitatory Amino Acid Antagonists.)|Drugs intended to prevent damage to the brain or spinal cord from ischemia, stroke, convulsions, or trauma. Some must be administered before the event, but others may be effective for some time after. They act by a variety of mechanisms, but often directly or indirectly minimize the damage produced by endogenous excitatory amino acids. (See all compounds classified as Neuroprotective Agents.)
aptiganel
Aptiganel Use and Manufacturing
Stroke and traumatic brain injury treatment (NMDA ion channel blocker).
Computed Properties
Molecular Weight:303.4
XLogP3:4.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:4
Exact Mass:303.173547683
Monoisotopic Mass:303.173547683
Topological Polar Surface Area:41.6
Heavy Atom Count:23
Complexity:406
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes