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Avridine

Avridine structure

CAS No:
35607-20-6
Formula:
C43H90N2O2
Chemical Name:
Avridine
Synonyms:
Ethanol,2,2′-[[3-(dioctadecylamino)propyl]imino]bis-;2,2′-[[3-(Dioctadecylamino)propyl]imino]bis[ethanol];N,N-Dioctadecyl-N′,N′-bis(2-hydroxyethyl)-1,3-diaminopropane;CP 20961;N,N-Dioctadecyl-N′,N′-bis(2-hydroxyethyl)propanediamine;Avridine;2,2′-((3-(Dioctadecylamino)propyl)azanediyl)diethanol;2-[3-(Dioctadecylamino)propyl-(2-hydroxyethyl)amino]ethanol
Categories:
Organic Chemistry > Amides

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Description

Off-White to Pale Yellow Solid

Avridine Basic Attributes

Molecular Weight：

667.196

Exact Mass：

667.19

UNII：

P9J7O7YNSW

DSSTox ID：

DTXSID70189078

HScode：

2922199090

Characteristics

PSA：

46.9

XLogP3：

12.48810

Appearance：

white to off-white

Density：

0.892g/cm3

Boiling Point：

717.6ºC at 760mmHg

Flash Point：

294.3ºC

Refractive Index：

1.478

Water Solubility：

DMSO: ≥5mg/mL (with warming to 60 °C for 5 minutes)

Storage Conditions：

Store at RT

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

RTECS Number：

KK7243000

Drug Information

MeSH：

Substances that augment, stimulate, activate, potentiate, or modulate the immune response at either the cellular or humoral level. The classical agents (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contain bacterial antigens. Some are endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Their mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy of many biological response modifiers is related to their antigen-specific immunoadjuvanticity. (See all compounds classified as Adjuvants, Immunologic.)|Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly. (See all compounds classified as Antiviral Agents.)|Agents that promote the production and release of interferons. They include mitogens, lipopolysaccharides, and the synthetic polymers Poly A-U and Poly I-C. Viruses, bacteria, and protozoa have been also known to induce interferons. (See all compounds classified as Interferon Inducers.)

MeSH Entry Terms：

avridine

Avridine Use and Manufacturing

A potent synthetic non-immunogenic adjuvant that can induce arthritis in most rat strains; immunomodulator and interferon-inducing.

Computed Properties

Molecular Weight:667.2
XLogP3:17
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:42
Exact Mass:666.70023012
Monoisotopic Mass:666.70023012
Topological Polar Surface Area:46.9
Heavy Atom Count:47
Complexity:504
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes