4-(4-aMino-6-chloropyriMidin-2-ylaMino)benzonitrile
-
4-(4-aMino-6-chloropyriMidin-2-ylaMino)benzonitrile
structure -
-
CAS No:
1398507-08-8
-
Formula:
C11H8ClN5
-
Chemical Name:
4-(4-aMino-6-chloropyriMidin-2-ylaMino)benzonitrile
-
Synonyms:
4-((4-Amino-6-chloropyrimidin-2-yl)amino)benzonitrile;4-(4-amino-6-chloropyrimidin-2-ylamino)benzonitrile;4-[(4-amino-6-chloropyrimidin-2-yl)amino]benzonitrile;Benzonitrile, 4-[(4-amino-6-chloro-2-pyrimidinyl)amino]-;CHEMBL4066948;SCHEMBL13730341;DTXSID60856126;QC-47;MFCD24682776;ZINC94568771
- Categories:
-
CAS No:
4-(4-aMino-6-chloropyriMidin-2-ylaMino)benzonitrile Basic Attributes
245.66772
245.047
DTXSID60856126
4-(4-aMino-6-chloropyriMidin-2-ylaMino)benzonitrile Use and Manufacturing
Preparation of 4-(4-amino-6-chloropyrimidin-2-ylamino)benzonitrile (Compound la)To a solution of 4-aminobenzonitrile (ABN; 7 g; 59.3 mmol) in 2-butanol (190 ml), 2, 6- dichloropyrimidin-4-amine (DCAP; 10.2 g; 62.2 mmol) was added at room temperature. The resulting suspension was heated to reflux (102 °C) and stirred for 20 hours. The suspension was then cooled to 20-25 °C and stirred for lhour at 20-25 °C. A solid was separated from the suspension by filtration and washed with 2-butanol (20 ml) and dried (2h/ 50 °C/ 10 mbar). Yield: 12.20 g (73.0 percent) of 4-(4-amino-6-chloropyrimidin-2-ylamino)benzonitrile hydrochloride.Purity (HPLC/ MS): 99.0 Area percentExample 3
Computed Properties
Molecular Weight:245.67
XLogP3:2.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:245.0468230
Monoisotopic Mass:245.0468230
Topological Polar Surface Area:87.6
Heavy Atom Count:17
Complexity:294
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Recommended Suppliers of 4-(4-aMino-6-chloropyriMidin-2-ylaMino)benzonitrile
-
![China]()
CN
2 YRS
Business licensed Certified factoryManufactory Supplier of 4-(Pentafluorothio)aniline,Pentafluoro,Pentafluorothio,Pentafluorosulfur,[4-(bromomethyl)phenyl]-pentafluoro-lambda6-sulfane,[4-(pentafluoro-sulfanyl)phenyl]acetic acidInquiryCAS No.: 1398507-08-8Grade: Industrial GradeContent: 95%
Learn More Other Chemicals
-
4-(4-aMino-6-chloropyriMidin-2-ylaMino)benzonitrile
91183-10-7
-
2-Bromophenacyl bromide, 90%
49851-55-0
-
1H-Indazol-7-ol
81382-46-9
-
6-Chloro-4-forMyl-nicotinic acid Formula
1031433-06-3
-
3-Hydroxy-2,4,5-trifluorobenzoic acid Formula
116751-24-7
-
2-Methyl-1-heptene Formula
15870-10-7
-
1-(3,5-Dinitrophenyl)ethanone Structure
14401-75-3
-
α-Amino-3-bromobenzeneacetic acid Structure
79422-73-4
-
What is 6-(BROMOMETHYL)-1,3-BENZOTHIAZOLE,97%
499770-85-3
-
What is ethyl 5-hydroxy-2-Methylnicotinate
60390-47-8
4-(4-aMino-6-chloropyriMidin-2-ylaMino)benzonitrile
SDSRequest for Quotation