 Home > Encyclopedia > Micheliolide

Micheliolide

Micheliolide structure

CAS No:
68370-47-8
Formula:
C15H20O3
Chemical Name:
Micheliolide
Synonyms:
Azuleno[4,5-b]furan-2(3H)-one,3a,4,5,7,8,9,9a,9b-octahydro-9-hydroxy-6,9-dimethyl-3-methylene-,(3aS,9R,9aS,9bS)-;Azuleno[4,5-b]furan-2(3H)-one,3a,4,5,7,8,9,9a,9b-octahydro-9-hydroxy-6,9-dimethyl-3-methylene-,[3aS-(3aα,9α,9aα,9bβ)]-;(3aS,9R,9aS,9bS)-3a,4,5,7,8,9,9a,9b-Octahydro-9-hydroxy-6,9-dimethyl-3-methyleneazuleno[4,5-b]furan-2(3H)-one;Micheliolide;2229044-01-1;2488402-49-7
Categories:
Pharmaceutical Intermediates > Bulk Drug Intermediates

Description

Micheliolide could effectively attenuate the high glucose-stimulated activation of NF-κB, the degradation of IκBα, and the expression of MCP-1, TGF-β1 and FN in rat mesangial cells (MCs).

Micheliolide is a sesquiterpene lactone.

Micheliolide Basic Attributes

Molecular Weight：

248.3175

Exact Mass：

248.32

DSSTox ID：

DTXSID20331787

Characteristics

PSA：

46.53000

XLogP3：

2.14

Density：

1.2±0.1 g/cm3

Melting Point：

131-133 °C

Boiling Point：

426.1±45.0 °C at 760 mmHg

Flash Point：

181.8±21.5 °C

Refractive Index：

1.555

Drug Information

MeSH Entry Terms：

micheliolide

Computed Properties

Molecular Weight:248.32
XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Exact Mass:248.14124450
Monoisotopic Mass:248.14124450
Topological Polar Surface Area:46.5
Heavy Atom Count:18
Complexity:462
Defined Atom Stereocenter Count:4
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Recommended Suppliers of Micheliolide

HANGZHOU LEAP CHEM CO., LTD. Contact Supplier

CN
5 YRS

Business licensed

Trader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives

Micheliolide

CAS No.: 68370-47-8

Content: 99.00%

Inquiry
Wuhan Pnq Int Trade Co., Ltd Contact Supplier

CN
3 YRS

Business licensed

Trader Supplier of Apigenin,PQQ,NMNH

Micheliolide

Unit Price: $100 /Unit EXW

CAS No.: 68370-47-8

Grade: Industrial Grade

Content: 99%

Inquiry