 Home > Encyclopedia > Dimethylcurcumin

Dimethylcurcumin

Dimethylcurcumin structure

CAS No:
52328-98-0
Formula:
C23H24O6
Chemical Name:
Dimethylcurcumin
Synonyms:
1,4,6-Heptatrien-3-one,1,7-bis(3,4-dimethoxyphenyl)-5-hydroxy-,(1E,4Z,6E)-;1,4,6-Heptatrien-3-one,1,7-bis(3,4-dimethoxyphenyl)-5-hydroxy-,(Z,E,E)-;(1E,4Z,6E)-1,7-Bis(3,4-dimethoxyphenyl)-5-hydroxy-1,4,6-heptatrien-3-one;Dimethylcurcumin;ASCJ 9;GO-Y 025;ASC-J 9
Categories:
Pharmaceutical Intermediates > Bulk Drug Intermediates

Description

ASC-J9 is an androgen receptor degradation enhancer that effectively suppresses castration resistant prostate cancer cell proliferation and invasion.

Dimethylcurcumin is a synthetic chemical compound that is loosely based on a compound found in curcumin. It is a novel anti-androgen that enhances androgen receptor degradation.

Dimethylcurcumin Basic Attributes

Molecular Weight：

396.439

Exact Mass：

396.43

EC Number：

2017-001-1

NSC Number：

734923

DSSTox ID：

DTXSID10200352

Characteristics

PSA：

74.2

XLogP3：

4.05

Density：

1.2±0.1 g/cm3

Melting Point：

129-130 °C @ Solvent: Methanol

Boiling Point：

588.6±50.0 °C at 760 mmHg

Flash Point：

201.8±23.6 °C

Refractive Index：

1.608

Drug Information

Drug Indication：

Investigated for use/treatment in acne and alopecia.

Computed Properties

Molecular Weight:396.4
XLogP3:4.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:9
Exact Mass:396.15728848
Monoisotopic Mass:396.15728848
Topological Polar Surface Area:74.2
Heavy Atom Count:29
Complexity:596
Defined Bond Stereocenter Count:3
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Recommended Suppliers of Dimethylcurcumin

Shandong zhishang chemical Co.,Ltd Contact Supplier

CN
5 YRS

Business licensed Certified factory

Manufactory Supplier of Dichloromethane,Linocaine hydrochloride

DimethylcurcuminCAS52328-98-0

CAS No.: 52328-98-0

Inquiry
Dingwang Technology (Wuhan) Co., Ltd. Contact Supplier

CN
5 YRS

Business licensed

Trader Supplier of API,nutrition supplements,plant extract,peptide,HCG

ASC-J9, Dimethylcurcumin 99% white powder 52328-98-0 Senwayer

CAS No.: 52328-98-0

Grade: Pharmaceutical Grade

Content: 99%

Inquiry
Henan Lihao Chem Plant Limited Contact Supplier

CN
5 YRS

Business licensed

Trader Supplier of PVC resin,pvc paste resin,melamine

high purity hot sale ASC-J9 99% high quality see COA KANBEI

CAS No.: 52328-98-0

Grade: Industrial Grade

Content: 99%

Inquiry
Shanghai Lonwin Chemical Co.,Ltd Contact Supplier

CN
3 YRS

Business licensed

Trader Supplier of CHEMICALS,REAGENTS

High quality Dimethylcurcumin CAS NO.52328-98-0

CAS No.: 52328-98-0

Grade: Pharmaceutical Grade

Content: 99%

Inquiry