Azafenidin
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Azafenidin
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CAS No:
68049-83-2
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Formula:
C15H13Cl2N3O2
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Chemical Name:
Azafenidin
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Synonyms:
1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one,2-[2,4-dichloro-5-(2-propyn-1-yloxy)phenyl]-5,6,7,8-tetrahydro-;1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one,2-[2,4-dichloro-5-(2-propynyloxy)phenyl]-5,6,7,8-tetrahydro-;2-[2,4-Dichloro-5-(2-propyn-1-yloxy)phenyl]-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyridin-3(2H)-one;Azafenidin;Milestone;Evolus;DPX-R 6447;Milestone (azafenidin herbicide)
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CAS No:
Description
Azafenidin is a triazolopyridine that is 5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one which is substituted at position 2 by a 2,4-dichloro-5-(prop-2-yn-1-yloxy)phenyl group. A protoporphyrinogen oxidase inhibitor, it is used as a herbicide to control weeds in fruit crops such as pineapple, citrus, melons, and grapes. Not approved for use within the European Union. It has a role as an EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor. It is a triazolopyridine, a terminal acetylenic compound and a dichlorobenzene.
Characteristics
45.1
2.68910
1.43g/cm3
168 °C
468.9ºC at 760 mmHg
237.4ºC
1.65
4.73e-05 M
7.50e-12 mmHg
LD50 in rats, mice, bobwhite quail, mallard duck (mg/kg): >5000, >5000, >2500, >2500 orally; in rabbits (mg/kg): >2000 dermally.; LC50 in rats, rainbow trout, blue gill sunfish (mg/l): >5.3, 33, 48 (Amuti)
Safety Information
61-48/22-62-50/53
53-45-60-61
T,N
P201, P202, P260, P273, P281, P308+P313, P314, P391, P405, P501
H360DF
|Danger|H360Df: May damage the unborn child; Suspected of damaging fertility [Danger Reproductive toxicity]|P201, P202, P260, P273, P281, P308+P313, P314, P391, P405, and P501|H360 (100%): May damage fertility or the unborn child [Danger Reproductive toxicity]|Aggregated GHS information provided by 13 companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.