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AZIDO-PEG-AMINE

AZIDO-PEG-AMINE structure

CAS No:
957486-82-7
Formula:
C22H46N4O10
Chemical Name:
AZIDO-PEG-AMINE
Synonyms:
AZIDO-PEG-AMINE;O-(2-AMINOETHYL)-O'-(2-AZIDOETHYL)HEPTAETHYLENE GLYCOL;O-(2-AMINOETHYL)-O'-(2-AZIDOETHYL)NONAETHYLENE GLYCOL;O-(2-AMINOETHYL)-O'-(2-AZIDOETHYL)PENTAETHYLENE GLYCOL;Azido-PEG-amine(n=6);20-Azido-3,6,9,12,15,18-hexaoxaeicosan-1-aMine;Amino-PEG7-azide;O-(2-Aminoethyl)-O'-(2-azidoethyl)pentaethylene glycol >=90% (oligomer purity)
Categories:
Pharmaceutical Intermediates > Bulk Drug Intermediates

Description

Azido-PEG6-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG6-amine is also a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].

AZIDO-PEG-AMINE Basic Attributes

Molecular Weight：

526.62

Exact Mass：

350.21700

DSSTox ID：

DTXSID60399240

HScode：

2929909090

Characteristics

PSA：

95.8

XLogP3：

0.50806

Storage Conditions：

2-8°C

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

36/37/38

safety instructions：

26-36

Marks：

Precautionary statement(s)：

P261-P305 + P351 + P338

Hazard Statements：

H315-H319-H335

AZIDO-PEG-AMINE Use and Manufacturing

A heterobifunctional polyethyleneglycol (PEG) derivative used in the preparation low-fouling, biofunctionalized, and biodegradable click capsules; a useful reagent used in the construction of intramolecular linkers.

Computed Properties

Molecular Weight:350.41
XLogP3:-0.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:20
Exact Mass:350.21653469
Monoisotopic Mass:350.21653469
Topological Polar Surface Area:95.8
Heavy Atom Count:24
Complexity:292
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Recommended Suppliers of AZIDO-PEG-AMINE

LAURENT.INC Contact Supplier

CN
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Trader Supplier of HEXAETHYLENE GLYCOL

N3-PEG6-CH2CH2NH2

CAS No.: 957486-82-7

Content: 98%

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