 Home > Encyclopedia > Buserelin Acetate

Buserelin Acetate

Buserelin Acetate structure

CAS No:
68630-75-1
Formula:
C60H86N16O13
Chemical Name:
Buserelin Acetate
Categories:
Active Pharmaceutical Ingredients > Hormones and the Endocrine System

Description

White Solid

Buserelin acetate is an organic molecular entity.|A potent synthetic analog of GONADOTROPIN-RELEASING HORMONE with D-serine substitution at residue 6, glycine10 deletion, and other modifications.

Buserelin Acetate Basic Attributes

Molecular Weight：

1299.499

Exact Mass：

1298.677

EC Number：

261-061-9

UNII：

13U86G7YSP

NSC Number：

725176

DSSTox ID：

DTXSID30218712

ATC Code：

L - Antineoplastic and immunomodulating agents

Characteristics

PSA：

478

Melting Point：

186-188°C

Safety Information

wgk germany：

safety instructions：

53-22-36/37/39-45

Marks：

Precautionary statement(s)：

P201, P202, P264, P270, P281, P301+P312, P308+P313, P330, P405, P501

Hazard Statements：

H302

GHS Classification：

|Danger|H302 (66.67%): Harmful if swallowed [Warning Acute toxicity, oral]|P201, P202, P264, P270, P281, P301+P312, P308+P313, P330, P405, and P501|Aggregated GHS information provided by 3 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|H302 (43.01%): Harmful if swallowed [Warning Acute toxicity, oral]|Aggregated GHS information provided by 93 companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

MeSH：

Compounds which increase the capacity to conceive in females. (See all compounds classified as Fertility Agents, Female.)

MeSH Entry Terms：

Acetate, Buserelin

Buserelin Acetate Use and Manufacturing

Gondadotropin-releasing hormone agonist, used to treat hormone-responsive cancers such as prostate and breast cancer. Synthetic nonapeptide agonist analog of LH-RH. Antineolpastic (hormonal).

Computed Properties

Molecular Weight:1299.5
Hydrogen Bond Donor Count:16
Hydrogen Bond Acceptor Count:17
Rotatable Bond Count:33
Exact Mass:1298.67715623
Monoisotopic Mass:1298.67715623
Topological Polar Surface Area:478
Heavy Atom Count:93
Complexity:2480
Defined Atom Stereocenter Count:9
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

Recommended Suppliers of Buserelin Acetate

Shaanxi Dideu Medichem Co. Ltd Contact Supplier

CN
5 YRS

Business licensed Certified factory

Manufactory Supplier of Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst,Chemical Materials,Chem&Pharm Intermediates,Organic Intermediates,Feed Additive

pGlu-His-Trp-Ser-Tyr-D-Ser(t-Bu)-Leu-Arg-Pro-NHEt, des-Gly10-[D-Ser[t-Bu]6]-LH-RH ethylamide

CAS No.: 68630-75-1

Inquiry