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Home > Encyclopedia > β,β-Dimethylacrylshikonin

β,β-Dimethylacrylshikonin

β,β-Dimethylacrylshikonin structure

β,β-Dimethylacrylshikonin 

structure
  • CAS No:

    24502-79-2

  • Formula:

    C21H22O6

  • Chemical Name:

    β,β-Dimethylacrylshikonin

  • Synonyms:

    2-Butenoic acid,3-methyl-,(1R)-1-(1,4-dihydro-5,8-dihydroxy-1,4-dioxo-2-naphthalenyl)-4-methyl-3-penten-1-yl ester;2-Butenoic acid,3-methyl-,1-(1,4-dihydro-5,8-dihydroxy-1,4-dioxo-2-naphthalenyl)-4-methyl-3-pentenyl ester,(R)-;2-Butenoic acid,3-methyl-,(1R)-1-(1,4-dihydro-5,8-dihydroxy-1,4-dioxo-2-naphthalenyl)-4-methyl-3-pentenyl ester;β,β-Dimethylacrylshikonin;Shikonin β,β-dimethylacrylate;Isoarnebin I;[(1R)-1-(5,8-Dihydroxy-1,4-dioxonaphthalen-2-yl)-4-methylpent-3-enyl] 3-methylbut-2-enoate

  • Categories:

    Pharmaceutical Intermediates  >  Bulk Drug Intermediates

Description

β,β-Dimethylacrylshikonin is a naphthoquinone derivative isolated from Arnebia nobilis, promotes angiogenesis by inducing eNOS, VEGF and HIF-1α expression through the PI3K-dependent pathway. Arnebin 1 has anti-tumor activity[1].

β,β-Dimethylacrylshikonin Basic Attributes

370.4

370.40

2916129000

Characteristics

101

4.45

1.3±0.1 g/cm3

103°C

653.2±55.0 °C at 760 mmHg

362.8±28.0 °C

1.616

Safety Information

22-24/25

EM9252400

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