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blasticidin A

blasticidin A structure

blasticidin A 

structure
  • CAS No:

    100513-53-9

  • Formula:

    C58H107NO23

  • Chemical Name:

    blasticidin A

  • Synonyms:

    blasticidin A;Blastidicin A;LS-44856;J-000152

blasticidin A Basic Attributes

1186.5

618.667847

Characteristics

451

20.45

0.8±0.1 g/cm3

610.9±23.0 °C at 760 mmHg

269.1±19.5 °C

1.458

Drug Information

blasticidin A

blasticidin A Use and Manufacturing

Blasticidin A is a high molecular weight tetramic acid with broad spectrum antifungal and antibacterial activity, first reported in 1955. Like many tetramic acids, blasticidin A is isolated as the stable calcium salt/complex. Blasticidin A and closely related aflastatin A are specific inhibitors of the production of the mycotoxin, aflatoxin, by Aspergillus parasiticus.

Computed Properties

Molecular Weight:1186.5
XLogP3:1.9
Hydrogen Bond Donor Count:20
Hydrogen Bond Acceptor Count:23
Rotatable Bond Count:40
Exact Mass:1185.72338866
Monoisotopic Mass:1185.72338866
Topological Polar Surface Area:451
Heavy Atom Count:82
Complexity:1920
Undefined Atom Stereocenter Count:25
Defined Bond Stereocenter Count:2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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