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Home > Encyclopedia > Lobenzarit disodium

Lobenzarit disodium

Lobenzarit disodium structure

Lobenzarit disodium 

structure
  • CAS No:

    64808-48-6

  • Formula:

    C14H10ClNO4.2Na

  • Chemical Name:

    Lobenzarit disodium

  • Synonyms:

    Benzoic acid,2-[(2-carboxyphenyl)amino]-4-chloro-,sodium salt (1:2);Benzoic acid,2-[(2-carboxyphenyl)amino]-4-chloro-,disodium salt;Disodium N-(2-carboxyphenyl)-4-chloroanthranilic acid;CCA;Lobenzarit sodium;Lobenzarit disodium;Lobenzarit disodium salt;Carfenil;82050-62-2

Description

Lobenzarit disodium is an aminobenzoic acid.

Lobenzarit disodium Basic Attributes

335.65

334.993713

7Z9SP74BXF

DTXSID8048606

2922509090

Characteristics

92.29000

0.88360

388 °C (decomp)

481ºC at 760 mmHg

244.7ºC

Safety Information

DG4975520

P264, P270, P301+P312, P330, P501

H302

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P264, P270, P301+P312, P330, and P501|The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.

Drug Information

Substances that augment, stimulate, activate, potentiate, or modulate the immune response at either the cellular or humoral level. The classical agents (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contain bacterial antigens. Some are endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Their mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy of many biological response modifiers is related to their antigen-specific immunoadjuvanticity. (See all compounds classified as Adjuvants, Immunologic.)|Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions.They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. (See all compounds classified as Anti-Inflammatory Agents, Non-Steroidal.)|Agents that suppress immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-CELLS or by inhibiting the activation of HELPER CELLS. While immunosuppression has been brought about in the past primarily to prevent rejection of transplanted organs, new applications involving mediation of the effects of INTERLEUKINS and other CYTOKINES are emerging. (See all compounds classified as Immunosuppressive Agents.)

2-((2-carboxyphenyl)amino)-4-chlorobenzoic acid

Lobenzarit disodium Use and Manufacturing

Antirheumatic.

Computed Properties

Molecular Weight:335.65
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:334.9937240
Monoisotopic Mass:334.9937240
Topological Polar Surface Area:92.3
Heavy Atom Count:22
Complexity:365
Covalently-Bonded Unit Count:3
Compound Is Canonicalized:Yes

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