1,2-Bis(p-tolylsulfonyl)hydrazine,N,Nμ-Ditosylhydrazine,4-Methylbenzenesulfonicacid2-[(4-methylphenyl)sulfonyl]hydrazide

Preparation of Λ/, Λ/'-ditosylhydrazineTo a mixture of p-toluenesulfonyl hydrazide (9.32 g, 50 mmol) and p-toluenesulfonyl chloride (14.3 g, 75 mmol) in CHTo a mixture of p-toluenesulfonyl hydrazide (9.32 g, 50 mmol) and p-toluenesulfonyl chloride (14.3 g, 75 mmol) in CHGeneral procedure: To a solution of 4-chlorobenzoyl chloride (5.0 ml, 39.1 mmol) and pyridine (3.5 mL, 43.3 mmol) inTHF (80 mL) was add hydrazine monohydrate (0.95 mL, 18.9 mmol) dropwise at 0 °C. Theprecipitate was collected by filtration, washed by THF and water, and dried in vacuo to give 2e (3.59g, 11.6 mmol, 61 percent) as a colorless crystal.General procedure: 7.6 g (100.0 mmol) of solid hydrazine (H3N + NHCO2-) and adipic acid (7.3 g, 50.0 mmol) were mixed in a mortar without a solvent for 10 minutes and stirred at 100 ° C for 5 hours. To confirm the structure and composition of the product produced in this process and analyzed using 400 MHz NMR (nuclear magnetic resonance) and elemental analysis) .As a result of the analysis, the product was adipohydrazide (C6H14N4O2), the conversion rate was 96percent or more, and the yield was 95percent or more. Yield (8.27 g, 96percent or more); The product was obtained in the same manner as in except that 8.61 g of 4-methylbenzenesulfonic acid was used instead of adipic acid. As a result of the analysis, the product was 4-methyl-N'-tosylbenzenesulfonohydrazide, the selectivity was 97percent, and the yield was 95percent. Yield: (8.08g, 95percent).

Molecular Weight:340.4
XLogP3:2.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:340.05514934
Monoisotopic Mass:340.05514934
Topological Polar Surface Area:109
Heavy Atom Count:22
Complexity:495
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes