BMS-599626
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BMS-599626
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CAS No:
873837-23-1
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Formula:
C27H27FN8O3.HCl
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Chemical Name:
BMS-599626
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Synonyms:
[4-[[1-[(3-Fluorophenyl)methyl]-1H-indazol-5-yl]amino]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]carbamic acid (3S)-3-morpholinylmethyl ester hydrochloride;BMS-599626 (AC480);BMS-599626 (Hydrochloride);BMS-599626 HCl
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CAS No:
BMS-599626 Use and Manufacturing
BMS-599626 is a highly selective pan-HERKinase inhibitor with IC50 of 20 and 30 nM for the inhibition of HER1and HER2, respectively.
Computed Properties
Molecular Weight:567.0
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:8
Exact Mass:566.1956926
Monoisotopic Mass:566.1956926
Topological Polar Surface Area:120
Heavy Atom Count:40
Complexity:828
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes
