BMS-690514
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BMS-690514
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CAS No:
859853-30-8
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Formula:
C19H24N6O2
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Chemical Name:
BMS-690514
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Synonyms:
BMS-690514;(3R,4R)-4-Amino-1-[[4-[(3-methoxyphenyl)amino]pyrrolo[2,1-f][1,2,4]triazin-5-yl]methyl]piperidin-3-ol;3-Piperidinol, 4-amino-1-[[4-[(3-methoxyphenyl)amino]pyrrolo[2,1-f][1,2,4]triazin-5-yl]methyl]-, (3R,4R)-;(3R,4R)-4-Amino-1-[[4-[(3...;BMS-690514(BMS-6690514);BMS690514/BMS-690514;(3R,4R)-4-Amino-1-[[4-[(3-methoxyphenyl)amino]pyrrolo-[2,1-f][1,2,4]triazin-5-yl]methyl]piperidin;BMS-6690514
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CAS No:
Description
BMS-690514 is a potent and orally active inhibitor of EGFR and VEGFR; has IC50s of 5, 20 and 60 nM for EGFR, HER 2 and HER 4, respectively.
BMS-690514 has been investigated for the treatment of Breast Cancer.
Computed Properties
Molecular Weight:368.4
XLogP3:0.7
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:5
Exact Mass:368.19607403
Monoisotopic Mass:368.19607403
Topological Polar Surface Area:101
Heavy Atom Count:27
Complexity:483
Defined Atom Stereocenter Count:2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
