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Home > Encyclopedia > 5-BroMo-6-hydroxypicolinic acid

5-BroMo-6-hydroxypicolinic acid

5-BroMo-6-hydroxypicolinic acid structure

5-BroMo-6-hydroxypicolinic acid 

structure
  • CAS No:

    1214385-51-9

  • Formula:

    C6H4BrNO3

  • Chemical Name:

    5-BroMo-6-hydroxypicolinic acid

  • Synonyms:

    5-Bromo-6-hydroxypicolinic acid;5-bromo-6-oxo-1,6-dihydropyridine-2-carboxylic acid;5-bromo-6-oxo-1H-pyridine-2-carboxylic acid;SCHEMBL15832302;CTK8B4440;KS-00000IHJ;DTXSID40735283;ANW-45042;MFCD24386919;ZINC77032004

5-BroMo-6-hydroxypicolinic acid Basic Attributes

218.00486

216.937454

DTXSID40735283

2933399090

Characteristics

66.4

0.8

2.0±0.1 g/cm3

218.5±28.7 °C

1.666

5-BroMo-6-hydroxypicolinic acid Use and Manufacturing

Bromine (115 g, 720 mmol) was added drop-wise to a suspension of 6-oxo-1, 6-dihydropyridine-2-carboxylic acid (25 g, 180 mmol) in acetic acid (400 mL). The reaction mixture was heated to 80° C. for 16 hours, whereupon it was concentrated to dryness under reduced pressure. The residue was triturated with tert-butyl methyl ether (200 mL) and filtered; the filter cake was washed with tert-butyl methyl ether (3×100 mL) to provide the product as a gray solid. Yield: 39.0 g, 179 mmol, 99percent.

Computed Properties

Molecular Weight:218.00
XLogP3:0.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:216.93746
Monoisotopic Mass:216.93746
Topological Polar Surface Area:66.4
Heavy Atom Count:11
Complexity:280
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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