1-Bromo-2-fluoro-4-propylbenzene

71 g (276 mmol) of the boron compound 3, 67 g (690 mmol) of potassium acetate and 5 g (7 mmol) of PdCl2-dppf are added to a solution of 50 g (230 mmol) of the bromide 2 in 590 ml of dioxane, and the mixture is warmed at 100 C. for 17 h. Water is added to the cooled batch, which is extracted with MTB ether. The organic phase is dried over sodium sulfate and evaporated. The residue is filtered through silica gel (n-heptane). The residue 4 obtained is employed in the subsequent step without further purification.

Molecular Weight:217.08
XLogP3:4.1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:215.99499
Monoisotopic Mass:215.99499
Heavy Atom Count:11
Complexity:116
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes