5-BROMO-4-FLUORO-2-HYDROXY-BENZALDEHYDE

Bromine (14.1 g, 88.3 mmol) in chloroform (25 mL) was added over a 10 minute period to a round bottom flask containing 4-fluoro-2-hydroxybenzaldehyde (13.6 g, 97.1 mmol) in chloroform (68 mL). This mixture was stirred at room temperature for 16 hours, and additional bromine (14.1 g) was added. The mixture was stirred for an additional 24 hours at room temperature. The mixture was then washed with 30percent aqueous sodium thiosulfate solution (2 X) to discharge the color, water, and then dried over sodium sulfate. The organics were concentrated under reduced pressure to give 5-bromo-4-fluoro-2- hydroxybenzaldehyde (21.3 g, 100percent).

Molecular Weight:219.01
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:217.93787
Monoisotopic Mass:217.93787
Topological Polar Surface Area:37.3
Heavy Atom Count:11
Complexity:153
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes