Atrimustine
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Atrimustine
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CAS No:
75219-46-4
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Formula:
C41H47Cl2NO6
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Chemical Name:
Atrimustine
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Synonyms:
Estra-1,3,5(10)-triene-3,17-diol (17β)-,3-benzoate 17-[2-[4-[4-[bis(2-chloroethyl)amino]phenyl]-1-oxobutoxy]acetate];Estra-1,3,5(10)-triene-3,17-diol (17β)-,3-benzoate 17-[[4-[4-[bis(2-chloroethyl)amino]phenyl]-1-oxobutoxy]acetate],(3β,5β)-;Estra-1,3,5(10)-triene-3,17-diol (17β)-,3-benzoate 17-[[4-[4-[bis(2-chloroethyl)amino]phenyl]-1-oxobutoxy]acetate];KM 2210;Bestrabucil;17β-Busramustine;Atrimustine
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CAS No:
Characteristics
82.1
9.7
1.1424 (rough estimate)
Oral-rat LD50: >6000 mg/kg; Oral-Mouse LD50:>10000 mg/kg
Drug Information
Substances that inhibit or prevent the proliferation of NEOPLASMS. (See all compounds classified as Antineoplastic Agents.)|Agents that suppress immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-CELLS or by inhibiting the activation of HELPER CELLS. While immunosuppression has been brought about in the past primarily to prevent rejection of transplanted organs, new applications involving mediation of the effects of INTERLEUKINS and other CYTOKINES are emerging. (See all compounds classified as Immunosuppressive Agents.)
bestrabucil
Computed Properties
Molecular Weight:720.7
XLogP3:9.7
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:17
Exact Mass:719.2780436
Monoisotopic Mass:719.2780436
Topological Polar Surface Area:82.1
Heavy Atom Count:50
Complexity:1120
Defined Atom Stereocenter Count:5
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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