Product
Supplier
Encyclopedia
Inquiry
Home > Encyclopedia > 1-Boc-1,2,5,6-tetrahydropyridine-3-carboxylic acid

1-Boc-1,2,5,6-tetrahydropyridine-3-carboxylic acid

1-Boc-1,2,5,6-tetrahydropyridine-3-carboxylic acid structure

1-Boc-1,2,5,6-tetrahydropyridine-3-carboxylic acid 

structure
  • CAS No:

    86447-11-2

  • Formula:

    C11H17NO4

  • Chemical Name:

    1-Boc-1,2,5,6-tetrahydropyridine-3-carboxylic acid

  • Synonyms:

    1-BOC-1,2,5,6-TETRAHYDROPYRIDINE-3-CARBOXYLIC ACID;1-(tert-butoxycarbonyl)-1,2,5,6-tetrahydropyridine-3-carboxylic acid;1-Boc-1,2,5,6-tetrahydropyridine-3-carboxylicacid;1-[(tert-butoxy)carbonyl]-1,2,5,6-tetrahydropyridine-3-carboxylic acid;1-[(2-methylpropan-2-yl)oxycarbonyl]-3,6-dihydro-2H-pyridine-5-carboxylic acid;PubChem12055;SCHEMBL2270068;CTK5F6661;KS-00000HCG;DTXSID70515792

  • Categories:

    Pharmaceutical Intermediates  >  Heterocyclic Compound

1-Boc-1,2,5,6-tetrahydropyridine-3-carboxylic acid Basic Attributes

227.26

227.115753

DTXSID70515792

2933399090

Characteristics

66.8

1

1.2±0.1 g/cm3

356.942ºC at 760 mmHg

169.7±27.9 °C

1.519

1-Boc-1,2,5,6-tetrahydropyridine-3-carboxylic acid Use and Manufacturing

1 (A) 5, 6-Dihydro-2H-pyridine-l, 3-dicarboxylic acid 1-tert-butyl ester; To a solution of l, 2, 5, 6-tetrahydro-pyridme-3-carboxylic acid hydrochloride (0.6 g, 3.66 mmol, ex Asinex) in water (15 mL) and dioxane (15 mL), IN NaOH was added to adjust the pH to 11. Diterbutyldicarbonate (0.88 g, 4.03 mmol) was then added in one portion and the reaction was kept under stirring overnight. The solvent was removed under reduced pressure and the resulting brown solid was dried in a vacuum oven at 5O0C overnight and used for the next step without further purification. LCMS (RT): 6.5 min (Method C); MS (ES+) gave m/z: 228.0, 128.0.

Computed Properties

Molecular Weight:227.26
XLogP3:1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:227.11575802
Monoisotopic Mass:227.11575802
Topological Polar Surface Area:66.8
Heavy Atom Count:16
Complexity:327
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Scan the QR Code to Share

Feedback & Suggestions
Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.