1-Boc-azetidine-2-carboxylic acid methyl ester
-
1-Boc-azetidine-2-carboxylic acid methyl ester
structure -
-
CAS No:
255882-72-5
-
Formula:
C10H17NO4
-
Chemical Name:
1-Boc-azetidine-2-carboxylic acid methyl ester
-
Synonyms:
MethylN-Boc-Azetidine-2-carboxylate;1,2-Azetidinedicarboxylic acid, 1-(1,1-dimethylethyl) 2-methyl ester;1-Boc-Azetidine-2-carboxy...;Methyl 1-Boc-azetidine-2-carboxylate;O1-tert-Butyl O2-methyl azetidine-1,2-dicarboxylate
-
CAS No:
1-Boc-azetidine-2-carboxylic acid methyl ester Basic Attributes
215.25
215.115753
DTXSID60564416
2933990090
Safety Information
|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.
1-Boc-azetidine-2-carboxylic acid methyl ester Use and Manufacturing
Isobutyl chloroformate (8.43 Ig, 61.7mmol) was added to a solution of iV-tert- butyloxycarbonylazetidin-2-yl carboxylic acid (12.42g, 61.7mmol) and N-methyl morpholine (6.23g, 61.7mmol) in anhydrous THF (20ml) cooled at -10°C under an nitrogen atmosphere, at such a rate to keep the reaction temperature below -8 To a solution of azetidine-2(S)-carboxylic acid, methyl ester hydrochloride salt (6.6 mmol, 1.0 g) in anhydrous dichloromethane (14 mL) was added di-tert-butyl dicarbonate (1.05 equiv; 6.9 mmol, 1.51 g), triethylamine (3.0 equiv; 19.8 mmol, 2.0 g, 2.76 mL), and 4-dimethyl-aminopyridine in that order at 25° C.
Computed Properties
Molecular Weight:215.25
XLogP3:1.2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:215.11575802
Monoisotopic Mass:215.11575802
Topological Polar Surface Area:55.8
Heavy Atom Count:15
Complexity:269
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Learn More Other Chemicals
-
Cyclopentanecarboxylic acid, 2-(hydroxyimino)-, methyl ester (9CI)
170016-09-8
-
3-CYCLOPROPYL-2-METHYL-3-OXO-PROPIONIC ACID ETHYL ESTER
21741-37-7
-
CYCLOPENTYL-CARBAMIC ACID PHENYL ESTER
58713-31-8
-
Cysteine, 2-methyl-, methyl ester (9CI) Formula
778548-47-3
-
D-Glucuronal 3,4-Diacetate Methyl Ester Formula
34296-99-6
-
2'-Deoxy-N-trimethylsilyl-3'-O-trimethylsilylcytidine 5'-phosphoric acid bis(trimethylsilyl) ester Formula
32645-72-0
-
4,6-Dichloro-1H-indole-2,3-dicarboxylic acid diethyl ester Structure
146012-24-0
-
2-[(2,6-Dichlorophenyl)sulfonyl]acetic acid ethyl ester Structure
1154228-17-7
-
What is Dibenzoic acid 2-ethylhexamethylene ester
25724-54-3
-
What is 1,4-DIBENZYL-7-PHENYL-6-THIOXO-1,4,7-TRIAZA-SPIRO[4.4]NON-8-ENE-9-CARBOXYLIC ACID ETHYL ESTER
885722-38-3
1-Boc-azetidine-2-carboxylic acid methyl ester
SDSRequest for Quotation