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Home > Encyclopedia > N-Succinimidyl 3-(4-hydroxyphenyl)propionate

N-Succinimidyl 3-(4-hydroxyphenyl)propionate

N-Succinimidyl 3-(4-hydroxyphenyl)propionate structure

N-Succinimidyl 3-(4-hydroxyphenyl)propionate 

structure
  • CAS No:

    34071-95-9

  • Formula:

    C13H13NO5

  • Chemical Name:

    N-Succinimidyl 3-(4-hydroxyphenyl)propionate

  • Synonyms:

    Benzenepropanoic acid,4-hydroxy-,2,5-dioxo-1-pyrrolidinyl ester;2,5-Pyrrolidinedione,1-[3-(4-hydroxyphenyl)-1-oxopropoxy]-;Succinimide,N-[(p-hydroxyhydrocinnamoyl)oxy]-;N-Succinimidyl 3-(4-hydroxyphenyl)propionate;3-(4-Hydroxyphenyl)propionic acid N-hydroxysuccinimide ester;NSC 240876;2,5-Dioxopyrrolidin-1-yl 3-(4-hydroxyphenyl)propanoate

  • Categories:

    Pharmaceutical Intermediates  >  Bulk Drug Intermediates

Description

white to off-white powder

N-Succinimidyl 3-(4-hydroxyphenyl)propionate Basic Attributes

263.25

263.25

251-818-1

240876

DTXSID50187673

2925190090

Characteristics

83.9

0.86990

white to off-white powder

1.4 g/cm3

132-133 °C(lit.)

448.8ºC

225.2ºC

1.606

soluble in water.

−20°C

Safety Information

NONH for all modes of transport

3

36/37/38

26-36

Xi

P261-P305 + P351 + P338

H315-H319-H335

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 40 companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

3-(4-hydroxyphenyl)propionic acid N-hydroxysuccinimide ester

N-Succinimidyl 3-(4-hydroxyphenyl)propionate Use and Manufacturing

After the reagent undergoes radioiodination reaction, it can be used as 125I acylating agent for protein and peptide.

Computed Properties

Molecular Weight:263.25
XLogP3:0.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:263.07937252
Monoisotopic Mass:263.07937252
Topological Polar Surface Area:83.9
Heavy Atom Count:19
Complexity:357
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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