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Home > Encyclopedia > 8-BROMOQUINOLINE-2-CARBOXYLIC ACID

8-BROMOQUINOLINE-2-CARBOXYLIC ACID

8-BROMOQUINOLINE-2-CARBOXYLIC ACID structure

8-BROMOQUINOLINE-2-CARBOXYLIC ACID 

structure
  • CAS No:

    914208-15-4

  • Formula:

    C10H6BrNO2

  • Chemical Name:

    8-BROMOQUINOLINE-2-CARBOXYLIC ACID

  • Synonyms:

    8-Bromoquinoline-2-carboxylic acid;SCHEMBL1723184;CTK8C2947;DTXSID60652822;8-bromo quinoline-2-carboxylic acid;ANW-69345;MFCD08690747;ZINC26439141;AKOS000320314;CS-W022562

8-BROMOQUINOLINE-2-CARBOXYLIC ACID Basic Attributes

252.06414

250.95800

DTXSID60652822

2933499090

Characteristics

50.2

2.7

1.732g/cm3

403.1ºC at 760 mmHg

197.6ºC

1.709

8-BROMOQUINOLINE-2-CARBOXYLIC ACID Use and Manufacturing

To a hot solution of selenium dioxide (100 g, 0.9 mol) in dioxane (1 L) was added 8-bromo-2-methylquinoline (28; 35.2 g, 0.16 mol) in one portion, and the mixture was heated under reflux for 3h, then filtered while hot. The mixture was concentrated and purified with silica gel column (pure dichloromethane) to give the aldehyde intermediate as a pale yellow solid (39g, yield 100percent). The solution of NaClO

Computed Properties

Molecular Weight:252.06
XLogP3:2.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:250.95819
Monoisotopic Mass:250.95819
Topological Polar Surface Area:50.2
Heavy Atom Count:14
Complexity:234
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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