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Home > Encyclopedia > Carbamic acid, [(1R)-1-methyl-3-oxopropyl]-, 1,1-dimethylethyl ester (9CI)

Carbamic acid, [(1R)-1-methyl-3-oxopropyl]-, 1,1-dimethylethyl ester (9CI)

Carbamic acid, [(1R)-1-methyl-3-oxopropyl]-, 1,1-dimethylethyl ester (9CI) structure

Carbamic acid, [(1R)-1-methyl-3-oxopropyl]-, 1,1-dimethylethyl ester (9CI) 

structure
  • CAS No:

    497861-77-5

  • Formula:

    C9H17NO3

  • Chemical Name:

    Carbamic acid, [(1R)-1-methyl-3-oxopropyl]-, 1,1-dimethylethyl ester (9CI)

  • Synonyms:

    (R)-tert-Butyl (4-oxobutan-2-yl)carbamate;TERT-BUTYL N-[(2R)-4-OXOBUTAN-2-YL]CARBAMATE;MFCD18835622;Carbamic acid, [(1R)-1-methyl-3-oxopropyl]-, 1,1-dimethylethyl ester (9CI);SCHEMBL73697;KS-00000LYE;(R)-tert-butyl 4-oxobutan-2-ylcarbamate;DS-18819;tert-butyl[(1r)-1-methyl-3-oxopropyl]carbamate

Carbamic acid, [(1R)-1-methyl-3-oxopropyl]-, 1,1-dimethylethyl ester (9CI) Basic Attributes

187.23618

187.121

Characteristics

55.4

0.8

1.000±0.06 g/cm3(Predicted)

279.9±23.0°C at 760 mmHg

Carbamic acid, [(1R)-1-methyl-3-oxopropyl]-, 1,1-dimethylethyl ester (9CI) Use and Manufacturing

C: (R)-tert-Butyl 4-oxobutan-2-ylcarbamate [00346] To a solution of (R)-tert-butyl 4-(methoxy(methyl)amino)-4-oxobutan-2- ylcarbamate (2.48 g, 10.1 mmol) in Et20 (25 niL) cooled to -5 °C was added dropwise a 2.0 M solution of LAH in THF (6.28 niL, 12.6 mmol). After the addition, the resulting slightly milky solution was stirred at 0 °C for 1.5 hr. The reaction mixture was quenched with 1 M aqueous KHSOD: (R, E)-Ethyl 5-(tert-butoxycarbonylamino)hex-2-enoate [00347] To a solution of

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