Fluocortin butyl
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Fluocortin butyl
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CAS No:
41767-29-7
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Formula:
C26H35FO5
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Chemical Name:
Fluocortin butyl
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Synonyms:
Pregna-1,4-dien-21-oic acid,6-fluoro-11-hydroxy-16-methyl-3,20-dioxo-,butyl ester,(6α,11β,16α)-;Butyl 6α-fluoro-11β-hydroxy-16α-methyl-3,20-dioxopregna-1,4-dien-21-oate;Butyl 6a-fluoro-11β-hydroxy-16α-methyl-3,20-dioxopregna-1,4-dien-21-oate;Butyl 6α-fluoro-11β-hydroxy-3,20-dioxo-16α-methyl-1,4-pregnadien-21-oate;Fluocortin butyl;Fluocortin butyl ester;Vaspit;Varlane;SH K 203;55749-92-3;73785-51-0
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CAS No:
Characteristics
80.7
4.3
195.1 °C
LD50 in mice, rats (g/kg): >4 orally and s.c. (Günzel)
D25 +136° (c = 0.5 in chloroform)
Drug Information
Drugs used to treat or prevent skin disorders or for the routine care of skin. (See all compounds classified as Dermatologic Agents.)|A group of CORTICOSTEROIDS that affect carbohydrate metabolism (GLUCONEOGENESIS, liver glycogen deposition, elevation of BLOOD SUGAR), inhibit ADRENOCORTICOTROPIC HORMONE secretion, and possess pronounced anti-inflammatory activity. They also play a role in fat and protein metabolism, maintenance of arterial blood pressure, alteration of the connective tissue response to injury, reduction in the number of circulating lymphocytes, and functioning of the central nervous system. (See all compounds classified as Glucocorticoids.)
fluocortin butyl ester
Fluocortin butyl Use and Manufacturing
A glucocorticoid with antiinflammatory activity with little or no side effects.
Computed Properties
Molecular Weight:446.6
XLogP3:4.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:446.24685237
Monoisotopic Mass:446.24685237
Topological Polar Surface Area:80.7
Heavy Atom Count:32
Complexity:877
Defined Atom Stereocenter Count:9
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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