2-(4-BROMOPHENYL)QUINOLINE

General procedure: In the present example, BODIPY-4 in was treated with BODIPY-8 having the following structural formula (the synthesis methodBODIPY-4), and the other procedure was the same as in to obtain quinoline in a yield of 84%.; Will replace the BODIPY organic photocatalyst(0.35 mg, 0.0005 mmol), TBAI (3.7 mg, 0.01 mmol), 1, 2, 3, 4-tetrahydroquinoline (67 mg, 0.5 mmol, Provided by Shanghai Sain Chemical Technology Co., Ltd.), N, N-dimethylformamide (5 mL) was added to the light parallel reaction tube, the oxygen balloon was bubbled for 10 minutes, the cork was screwed, the 5W blue LED was opened and the reaction was stirred at 60 C for 4 hours To the mixture was added 20 mL of saturated brine, and then extracted with 20 mL of ethyl acetate three times. The organic phase was collected, dried over anhydrous Na2SO4, filtered, and the solvent was removed by a rotary evaporator. Column chromatography gave a colorless oily liquid Quinoline 50 mg, the yield was 80%, and the spectral data were

Molecular Weight:284.15
XLogP3:4.6
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:282.99966
Monoisotopic Mass:282.99966
Topological Polar Surface Area:12.9
Heavy Atom Count:17
Complexity:247
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes