4-Azido-1-butanamine
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4-Azido-1-butanamine
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CAS No:
88192-20-5
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Formula:
C4H10N4
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Chemical Name:
4-Azido-1-butanamine
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Synonyms:
1-Butanamine,4-azido-;4-Azido-1-butanamine;4-Azidobutylamine;1-Azido-4-aminobutane;2138426-40-9
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CAS No:
Description
4-Azidobutylamine is a PROTAC linker, which refers to the alkyl chain composition. 4-Azidobutylamine can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Computed Properties
Molecular Weight:114.15
XLogP3:0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:114.090546336
Monoisotopic Mass:114.090546336
Topological Polar Surface Area:40.4
Heavy Atom Count:8
Complexity:84
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes