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Butriptyline

Butriptyline structure

Butriptyline 

structure
  • CAS No:

    35941-65-2

  • Formula:

    C21H27N

  • Chemical Name:

    Butriptyline

  • Synonyms:

    5H-Dibenzo[a,d]cycloheptene-5-propanamine,10,11-dihydro-N,N,β-trimethyl-;5H-Dibenzo[a,d]cycloheptene-5-propanamine,10,11-dihydro-N,N,β-trimethyl-,(±)-;10,11-Dihydro-N,N,β-trimethyl-5H-dibenzo[a,d]cycloheptene-5-propanamine;Butriptyline;10,11-Dihydro-N,N,β-trimethyl-5H-dibenzo[a,d]cycloheptene-5-propylamine;10,11-Dihydro-N,N,β-trimethyl-5H-dibenzo[ed]cycloheptene-5-propanamine;Butriptylene;15686-37-0

Description

Oil


Butriptyline is an organic tricyclic compound.|Butriptyline is a tricyclic antidepressant which has been used in Europe since 1974. It is the isobutyl side chain homologue of amitriptyline.

Butriptyline Basic Attributes

293.44578

293.45

DTXSID6022715

N - Nervous system

2921499090

Characteristics

3.2

5.1

0.9665 (rough estimate)

180-185 °C @ Press: 1 Torr

Thermal decomposition to emit toxic nitrogen oxide fumes

Safety Information

III

6.1(b)

1851

Warehouse ventilated, low temperature and dry

Toxicity

Side effects of tricyclic antidepressants include dry mouth, sour or metallic taste, constipation, retention of urine, blurred vision and changes in focusing, palpitations, and fast heart beat. Gastrointestinal disturbances (including nausea and vomiting), drowsiness, tremor, low blood pressure when standing, dizziness, sweating, weakness and fatigue, incoordination, epilepsy-like seizures, and speech difficulties may occur.

Drug Information

Mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. Several MONOAMINE OXIDASE INHIBITORS are useful as antidepressants apparently as a long-term consequence of their modulation of catecholamine levels. The tricyclic compounds useful as antidepressive agents (ANTIDEPRESSIVE AGENTS, TRICYCLIC) also appear to act through brain catecholamine systems. A third group (ANTIDEPRESSIVE AGENTS, SECOND-GENERATION) is a diverse group of drugs including some that act specifically on serotonergic systems. (See all compounds classified as Antidepressive Agents.)|Agents that alleviate ANXIETY, tension, and ANXIETY DISORDERS, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. ADRENERGIC BETA-ANTAGONISTS are commonly used in the symptomatic treatment of anxiety but are not included here. (See all compounds classified as Anti-Anxiety Agents.)

10,11-dihydro-N,N,beta-trimethyl-5H-dibenzo(a,d) cycloheptane-5-propylamine

Butriptyline Use and Manufacturing

Antidepressant

Computed Properties

Molecular Weight:293.4
XLogP3:5.1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:4
Exact Mass:293.214349865
Monoisotopic Mass:293.214349865
Topological Polar Surface Area:3.2
Heavy Atom Count:22
Complexity:313
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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