(4-Bromophenyl)-tert-butoxycarbonylaminoacetic acid methyl ester

Intermediate 1: tert-butoxycarbonylamino-[4-(pyridin-4-ylcarbamoyl)-phenyl]-acetic acid.; Amιno-(4-bromo-phenyl)-acetιc acid (3 g) was suspended in a mixture of concentrated HCI (10 ml) and MeOH (10 ml) The reaction mixture was stirred at room temperature (RT) for 2 days The white precipitate was filtered off and dried Amιno-(4-bromo-phenyl)-acetic acid methyl ester was obtained as a white powder (49 percent yield) Amιno-(4-bromo-phenyl)-acetιc acid methyl ester (1 8 g) was suspended in acetone (15 ml) 1 M NaGeneral procedure: The amino acid (1.0 mmol, 1.0 eq) was dispersed in MeOH (1.0 mL per 0.21 mmol of amino acid) with concd H

Molecular Weight:344.20
XLogP3:3.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:343.04192
Monoisotopic Mass:343.04192
Topological Polar Surface Area:64.6
Heavy Atom Count:20
Complexity:346
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes