2-(3-BROMO-4-METHOXYPHENYL)PYRIDINE

2- (4-methoxyphenyl) pyridine (I-b) (56 mg, 0.3 mmol), N-bromosuccinimide (II) (108 mg, 0.6 mmol), Was dissolved in N, N-dimethylformamide (0.2 M, 1.5 mL)(1, 5-cyclooctadiene) ruthenium dichloride (8 mg, 10 molpercent) was added and reacted at 150 ° C for 24 hours, The mixture was extracted with ethyl acetate (20 mL) and washed with water (10 mL × 3). The organic phase was dried over anhydrous sodium sulfate and filtered. The solvent was removed by spin column and the crude product was purified by column chromatography to give (3-bromo- ) Pyridine (III-b) 72 mg as a colorless oil, yield: 90percent.

Molecular Weight:264.12
XLogP3:3.2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:262.99458
Monoisotopic Mass:262.99458
Topological Polar Surface Area:22.1
Heavy Atom Count:15
Complexity:200
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes