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Home > Encyclopedia > 3-BROMO-7-NITROINDAZOLE

3-BROMO-7-NITROINDAZOLE

3-BROMO-7-NITROINDAZOLE structure

3-BROMO-7-NITROINDAZOLE 

structure
  • CAS No:

    74209-34-0

  • Formula:

    C7H4BrN3O2

  • Chemical Name:

    3-BROMO-7-NITROINDAZOLE

  • Synonyms:

    3-BroMo-7-nitro-1H-indazo...;1H-INDAZOLE,3-BROMO-7-NITRO-;BRNI;7-NITROINDAZOLE, 3-BROMO-;3-BROMO-7-NITROINDAZOLE;3-BROMO-7-NITRO-1H-INDAZOLE;3-Bromo-7-nitroindazole, 98+%

Description

3-Bromo-7-nitroindazole is a more potent and selective inhibitor of neuronal nitric oxide synthase (nNOS) than eNOS or inducible nitric oxide synthase (iNOS). 3-Bromo-7-nitroindazole affects the intercellular messenger nitric oxide (NO) synthesis throughout the body and brain[1].

3-BROMO-7-NITROINDAZOLE Basic Attributes

242.03

240.948685

DTXSID90274319

2933990090

Characteristics

74.5

2.4

light yellow powder

2.0±0.1 g/cm3

175-185 °C

182°C

218.3±23.2 °C

1.764

ethanol: 25 mg/mL

2-8°C

Safety Information

IRRITANT

NONH for all modes of transport

3

60

53-22-36/37/39-45

T

Harmful to reproduction

P201-P308 + P313

H360

|Danger|H360 (100%): May damage fertility or the unborn child [Danger Reproductive toxicity]|P201, P202, P281, P308+P313, P405, and P501|Aggregated GHS information provided by 38 companies from 1 notifications to the ECHA C&L Inventory.

Drug Information

3-Br-7-NI

3-BROMO-7-NITROINDAZOLE Use and Manufacturing

A more potent inhibitor of rat cerebellar nitric oxide synthase than 7-nitroindazole

Computed Properties

Molecular Weight:242.03
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Exact Mass:240.94869
Monoisotopic Mass:240.94869
Topological Polar Surface Area:74.5
Heavy Atom Count:13
Complexity:220
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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