 Home > Encyclopedia > 4-[3-(5-BROMO-2-PROPOXYPHENYL)-5-(4-CHLOROPHENYL)-1H-PYRROL-2-YL]PYRIDINE

4-[3-(5-BROMO-2-PROPOXYPHENYL)-5-(4-CHLOROPHENYL)-1H-PYRROL-2-YL]PYRIDINE

4-[3-(5-BROMO-2-PROPOXYPHENYL)-5-(4-CHLOROPHENYL)-1H-PYRROL-2-YL]PYRIDINE structure

CAS No:
191034-25-0
Formula:
C24H20BrClN2O
Chemical Name:
4-[3-(5-BROMO-2-PROPOXYPHENYL)-5-(4-CHLOROPHENYL)-1H-PYRROL-2-YL]PYRIDINE
Synonyms:
2-(4-pyridyl)-5-(4-chlorophenyl)-3-(5-bromo-2-propyloxyphenyl)pyrrole;L 168,049;L 168049;L-168,049;L-168049;Glucagon Receptor Antagonist II;4-[3-(5-bromo-2-propoxyphenyl)-5-(4-chlorophenyl)-1H-pyrrol-2-yl]pyridine;CHEMBL351772

Request for Quotation

Description

4-[3-(5-bromo-2-propoxyphenyl)-5-(4-chlorophenyl)-1H-pyrrol-2-yl]pyridine is a member of pyrroles.

4-[3-(5-BROMO-2-PROPOXYPHENYL)-5-(4-CHLOROPHENYL)-1H-PYRROL-2-YL]PYRIDINE Basic Attributes

Molecular Weight：

467.7854

Exact Mass：

466.045

DSSTox ID：

DTXSID10415520

Characteristics

PSA：

37.9

XLogP3：

6.8

Density：

1.367g/cm3

Boiling Point：

542.3ºC at 760mmHg

Flash Point：

281.8ºC

Refractive Index：

1.626

Storage Conditions：

Store at RT

Vapor Pressure：

2.83E-11mmHg at 25°C

Drug Information

MeSH Entry Terms：

2-(4-pyridyl)-5-(4-chlorophenyl)-3-(5-bromo-2-propyloxyphenyl)pyrrole

4-[3-(5-BROMO-2-PROPOXYPHENYL)-5-(4-CHLOROPHENYL)-1H-PYRROL-2-YL]PYRIDINE Use and Manufacturing

Very potent and selective, non-competitive antagonist of the human glucagon receptor (hGR). Binds with high affinity to human GR (IC 50 = 3.7 nM), and moderate affinity to murine and canine GRs (IC 50 values are 63 and 60 nM respectively). In contrast, displays poor affinity for rat, guinea pig, and rabbit glucagon receptors (IC 50 > 1 μ M). In functional studies, inhibits glucagon-stimulated cAMP synthesis in CHO cells expressin

Computed Properties

Molecular Weight:467.8
XLogP3:6.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:6
Exact Mass:466.04475
Monoisotopic Mass:466.04475
Topological Polar Surface Area:37.9
Heavy Atom Count:29
Complexity:495
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Hot Searches: retatrutide wholesale; polyethylene price 2021; chemical manufacturing news; best online peptide store; dapagliflozin propanediol 10 mg tablet; sodium dichloroisocyanurate

Guide of 4-[3-(5-BROMO-2-PROPOXYPHENYL)-5-(4-CHLOROPHENYL)-1H-PYRROL-2-YL]PYRIDINE

Description
Basic Attributes
Characteristics
Drug Information
Use and Manufacturing
Computed Properties

4-[3-(5-BROMO-2-PROPOXYPHENYL)-5-(4-CHLOROPHENYL)-1H-PYRROL-2-YL]PYRIDINE

SDS

Request for Quotation



Feedback & Suggestions

Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.