6-Carboxytetramethylrhodamine succinimidyl ester
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6-Carboxytetramethylrhodamine succinimidyl ester
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CAS No:
150810-69-8
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Formula:
C29H25N3O7
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Chemical Name:
6-Carboxytetramethylrhodamine succinimidyl ester
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Synonyms:
6-TAMRA, SE [6-Carboxytetramethylrhodamine, succinimidyl ester] *Single isomer*;6-Carboxy-tetramethylrhodamine N-succinimidyl ester, for fluorescence;6-CARBOXYTETRAMETHYLRHODAMINE, SUCCINIMIDE ESTER;6-CARBOXYTETRAMETHYLRHODAMINE, SUCCINIMIDYL ESTER;6-TAMRA SE;6-TAMRA-SEor6-TAMRA-NHS;2-(6-(Dimethylamino);-3-(dimethyliminio)
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CAS No:
Description
6-TAMRA-SE is an amine-reactive form of tetramethylrhodamine; one of the traditional fluorophores used for automated DNA sequencing.
TAMRA (tetramethylrhodamine) is a xanthene dye with a fluorescence maximum at 567 nm.This product is an N-Hydroxysuccinimide (NHS)-ester of TAMRA dye. Pure 6-isomer. TAMRA NHS-ester readily reacts with various amines and is used to generate fluorescently labeled proteins, peptides, antibodies, and other biomolecules.
Appearance: Purple solidex/em: 550/576 nm (MeOH/PBS)Extinction coefficient (ε): 90000 Lmol1cm1Quantum yield (Φ): 0.1
6-Carboxytetramethylrhodamine succinimidyl ester Basic Attributes
527.53
527.169250
DTXSID40376332
Dark purple to black
6-Carboxytetramethylrhodamine succinimidyl ester Use and Manufacturing
Amine-reactive form of 6-carboxytetramethylrhodamine single isomer used for labeling of peptides and aminoglycoside antibiotics. It is also most commonly used in automated DNA sequencing.
6-TAMRA SE is a fluorescent indicator.
Computed Properties
Molecular Weight:527.5
XLogP3:2.6
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:5
Exact Mass:527.16925015
Monoisotopic Mass:527.16925015
Topological Polar Surface Area:119
Heavy Atom Count:39
Complexity:1140
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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6-Carboxytetramethylrhodamine succinimidyl ester
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